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In vivo — у перекладі з латині: у живому ( … In vivo — у перекладі з латині: у живому (чи на живому) — означає, що подія відбувається всередині організму. У науці in vivo означає експерименти, що проводяться на живих тканинах і цілих організмах чи всередині них. Прикладами експериментів in vivo можуть бути експерименти на лабораторних тваринах чи клінічні випробовування.орних тваринах чи клінічні випробовування.
, Η λατινογενής έκφραση in vivo, (που ελληνι … Η λατινογενής έκφραση in vivo, (που ελληνικά αποδίδεται «ἐν ζωῄ») αναφέρεται σε ότι λαμβάνει χώρα μέσα σε έναν έμβιο οργανισμό. Ιδιαίτερα στη Βιολογία ο όρος αναφέρεται σε πειράματα που πραγματοποιούνται σε ιστούς εντός ζώντος οργανισμού σε αντιδιαστολή με τον όρο in vitro (= «σε δοκιμαστικό σωλήνα»), που αναφέρεται σε αντίστοιχα πειράματα αποσπασμένων μερών εκτός του ζωντανού οργανισμού, καθώς και σε έρευνες και πειράματα ex vivo.
* Γενικά οι κλινικές δοκιμές και τα πειράματα με ζώα είναι μορφές έρευνας in vivo. Ο τύπος αυτός έρευνας αποτελεί έναν ολιστικό τρόπο πειραματισμού. Προσφέρεται για μελέτες περισσότερο από τις in vitro μελέτες, λόγω του ότι δίνει πιστότερα, και πλέον ασφαλή και αξιόπιστα σε χρήση αποτελέσματα σε ένα πείραμα. Παρόλα αυτά, εκτός του ότι τα πειράματα του είδους αυτού έχουν υψηλότερο κόστος πραγματοποίησης, σε πολλές περιπτώσεις και πολύ συχνά, (ιδιαίτερα πρόσφατα), συναντούν τεράστιες δυσκολίες εκτέλεσης λόγω αναφυομένων θεμάτων κοινωνικής ηθικής και ζωοφιλίας.
* Σημαντικότερα "in vivo" πειράματα είναι εκείνα της "in vivo mutagenesis" δηλαδή της δημιουργίας "μετάλλαξης εν ζωῄ". Επίσης στις "in vivo" έρευνες και μελέτες υπάγονται οι διάφορες μετρήσεις σφυγμού, θερμοκρασίας σώματος, οι , μερικώς οι ακτινογραφίες κ.ά. Σημειώνεται ότι η ελληνική έκφραση "εν ζωῄ" χρησιμοποιείται κυρίως σε ανθρώπους που μετά από κάποιο συμβάν διατηρούνται στη ζωή, καθώς και σε πράξεις ανθρώπων προ του θανάτου τους. Αντίθετη ελληνική έκφραση είναι "μετά θάνατον".ετη ελληνική έκφραση είναι "μετά θάνατον".
, في الجسم الحي أو في الوسط الحيوي (باللاتين … في الجسم الحي أو في الوسط الحيوي (باللاتينية: in vivo) يطلق هذا المصطلح على العمليات والتفاعلات الحيوية وأحيانا التعديلات التي تحدث على الكائن الحي إما في بيئته أو داخل جسمه. فعلى سبيل المثال إذا كان النبات ينمو في بيئته الطبيعية في التربة بنفس الظروف يكون ناميًا في الحيوية، أما إذا كان ينمو في المعمل أو في المصانع في بيئة صناعية وظروف مشابهة لظروفه الطبيعية فهو ينمو صناعيًا «في المختبر» in vitro.ية فهو ينمو صناعيًا «في المختبر» in vitro.
, In vivo (en latin : « au sein du vivant ») … In vivo (en latin : « au sein du vivant ») est une expression latine qualifiant des recherches ou des examens pratiqués sur un organisme vivant, par opposition à in vitro ou ex vivo. Les essais cliniques sont une forme de recherche in vivo, en l'occurrence sur des humains. In vivo permet la distinction par rapport aux recherches ou examens in vitro, qui sont effectués sur des organes, des tissus, des cellules, des composants de la cellule, des protéines, ou des biomolécules, et par in silico désignant une recherche ou un essai effectué au moyen de calculs complexes informatisés ou de modèles informatiques. informatisés ou de modèles informatiques.
, 생체내 또는 인 비보(라틴어: In vivo, "세포 안에서")는 살아 있는 세포 안에서 직접 생화학, 생물학 실험 등을 하는 것을 일컫는다.
, In vivo (Latijn: binnen (in het) leven) is een proces dat in het complete levende lichaam van een organisme plaatsvindt. Verwante termen zijn in vitro (in glas) voor reageerbuistechnieken en in silico (in silicium) voor computersimulaties.
, In vivo (Latín: dentro de lo vivo) signifi … In vivo (Latín: dentro de lo vivo) significa "que ocurre o tiene lugar dentro de un organismo". En ciencia, in vivo se refiere a experimentación hecha dentro o en el tejido vivo de un organismo vivo, por oposición a uno parcial o muerto (denominado in vitro). Pruebas con animales y los ensayos clínicos son formas de investigación in vivo.nicos son formas de investigación in vivo.
, In vivo syftar på biologiska processer i l … In vivo syftar på biologiska processer i levande celler och vävnader när de befinner sig på sin naturliga plats i hela organismer, särskilt om processer som används i vetenskapliga försök och kliniska tester. Ett vanligt begrepp inom den gentekniska grenen genterapi. Experiment som genomförs "in vivo" genomförs i djur eller människor (från latin, ungefär: "i den levande organismen"), till skillnad från ex vivo, in vitro, eller in silico (osv.: se länkar nedan). Begreppet används i tal och skrift inom biologisk och medicinsk forskning för att förmedla att experimentet genomförts i en levande experimentmodell. Tills nyligen har även denna term, som många Latinska termer, använts kursiverat (in vivo) men idag tillåts det ofta okursiverat eftersom begreppet är vedertaget såväl på svenska som engelska. Av etiska skäl finns anledning att minimera in vivo-forskning (se exempelvis 3R-principerna inom djurforskningsetiken), men idag kan preklinisk forskning inte genomföras helt utan att även forska in vivo. Många processer på cellulär nivå påverkar även vävnader, organ, eller kroppens olika system, vilket gör att en undersökning på hela organismer är viktig för att säkerställa effekt och säkerhet av potentiella kliniska interventioner. In vivo-forskning på människor följer Helsingforsdeklarationen och måste i Sverige godkännas av etikprövningsmyndigheten.ige godkännas av etikprövningsmyndigheten.
, In vivo (łac. „na żywym”) – termin stosowany zazwyczaj przy opisywaniu badań biologicznych, odnosi się do czegoś, co ma miejsce wewnątrz żywego organizmu – w ustroju żywym.
, In vivo (в буквальном переводе с лат. — «в … In vivo (в буквальном переводе с лат. — «в (на) живом»), то есть «внутри живого организма» или «внутри клетки». В науке in vivo обозначает проведение экспериментов на (или внутри) живой ткани при живом организме. Такое использование термина исключает использование части живого организма (так, как это делается при тестах in vitro) или использование мёртвого организма. Тестирование на животных и клинические испытания являются формами исследования in vivo.ния являются формами исследования in vivo.
, La locuzione latina in vivo, tradotta lett … La locuzione latina in vivo, tradotta letteralmente, significa nel vivente. La locuzione è usata per indicare fenomeni biologici riprodotti in un organismo vivente e non in provetta.Al contrario, se il fenomeno biologico si riproduce in provetta, si dice "in vitro", mentre se si riproduce in una simulazione matematica al computer si dice "in silico". In poche parole, il termine in vivo viene usato per cellule "vive", facenti parte di un organismo vivente; mentre il termine "in vitro" viene utilizzato per cellule di una coltura in laboratorio. Nella ricerca scientifica, l'osservazione di fenomeni in vivo è spesso ritenuta più attinente alla realtà fattuale rispetto alle riproduzioni in vitro, sebbene queste ultime siano altrettanto utili perché permettono di analizzare un fenomeno singolo, isolandolo dal contesto che potrebbe creare un rumore di fondo troppo elevato per poter distinguere il fenomeno in maniera chiara.distinguere il fenomeno in maniera chiara.
, In vivo és una expressió llatina que s'utilitza per descriure experiments químics, físics o farmacològics que tenen lloc dins d'un organisme viu, per oposició als que es duen a terme en un ambient artificial (in vitro).
, Als in vivo (lateinisch für ‚im Lebendigen … Als in vivo (lateinisch für ‚im Lebendigen‘) bezeichnet man in der Wissenschaft Prozesse, die im lebendigen Organismus ablaufen. Im Gegensatz dazu werden Abläufe, die in künstlicher Umgebung (z. B. im Reagenzglas) oder ganz allgemein außerhalb lebender Organismen stattfinden, mit dem Begriff in vitro belegt. Man sagt also beispielsweise, dass eine biochemische Reaktion entweder in vivo oder in vitro abläuft. Forschungsergebnisse (z. B. Wirkstoffentwicklung), die unter (Labor-)Bedingungen in vitro erzielt werden, lassen sich unter den komplexeren Bedingungen im lebenden Organismus in vivo nicht unbedingt bestätigen. In-vivo-Studien sind daher wissenschaftliche Praxis zur Überprüfung von in vitro erlangten Erkenntnissen.fung von in vitro erlangten Erkenntnissen.
, In vivo je latinský termín (in v, vivus ži … In vivo je latinský termín (in v, vivus živý) užívaný v biologii a medicíně. Znamená doslovně „v živém“, míněno:
* v živém organismu, lidském nebo zvířecím; může se týkat jak pokusu, tak skutečného průběhu určitého děje nebo nemoci;
* za života organismu, např. studium biologických pochodů za života organismu;
* v přirozených podmínkách, např. pozorování organismů (příp. jejich orgánů, ještě jednodušších biologických složek a látek) v přirozeném prostředí. Označení in vivo je antonymem k in vitro (pozorování v umělých, např. laboratorních podmínkách). Jak v české, tak světové odborné literatuře včetně anglické je zvykem psát termín in vivo kurzívou.ké je zvykem psát termín in vivo kurzívou.
, In vivo為拉丁文「在活體內」之意。在科學文献中，in vivo常指進行於完整且存活的個體內的組織的實驗，以区别在生物体上移除下来的組織或死亡的组织上进行的实验（对应的拉丁文為in vitro）。
, Studies that are in vivo (Latin for "withi … Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism. This is not to be confused with experiments done in vitro ("within the glass"), i.e., in a laboratory environment using test tubes, Petri dishes, etc. Examples of investigations in vivo include: the pathogenesis of disease by comparing the effects of bacterial infection with the effects of purified bacterial toxins; the development of non-antibiotics, antiviral drugs, and new drugs generally; and new surgical procedures. Consequently, animal testing and clinical trials are major elements of in vivo research. In vivo testing is often employed over in vitro because it is better suited for observing the overall effects of an experiment on a living subject. In drug discovery, for example, verification of efficacy in vivo is crucial, because in vitro assays can sometimes yield misleading results with drug candidate molecules that are irrelevant in vivo (e.g., because such molecules cannot reach their site of in vivo action, for example as a result of rapid catabolism in the liver). The English microbiologist Professor Harry Smith and his colleagues in the mid-1950s found that sterile filtrates of serum from animals infected with Bacillus anthracis were lethal for other animals, whereas extracts of culture fluid from the same organism grown in vitro were not. This discovery of anthrax toxin through the use of in vivo experiments had a major impact on studies of the pathogenesis of infectious disease. The maxim in vivo veritas ("in a living thing [there is] truth") is a play on in vino veritas, ("in wine [there is] truth"), a well-known proverb. [there is] truth"), a well-known proverb.
, in vivo（イン・ビボ）とは、「生体内で」を意味する用語であり、学術論文などにもしばしば登場する。由来はラテン語。
, in vivo (en-organisma) (el la latina en vi … in vivo (en-organisma) (el la latina en vivulo) estas latin-devena scienca faktermino uzata por tiuj procezoj, kiuj okazas en vivanta organismo. Oni nomas tiun procezon, kiu okaza male, en artefarita medio (ekz. en ), - tio estas tute ekster la vivanta organismo - in vitro (ekster-organisma). Oni povas diri, ke iu biokemia reago okazas aŭ in vivo aŭ in vitro. Ĉar rezultoj de la ekster-organismaj eksperimentoj ne ĉiam respegulas la kondiĉojn de la en-organismaj eksperimentoj, tiel oni devas kontroli tiujn per en-organismaj eksperimentoj.oli tiujn per en-organismaj eksperimentoj.
, In vivo (em latim: dentro do vivo) signifi … In vivo (em latim: dentro do vivo) significa "que ocorre ou tem lugar dentro de um organismo ou em tecido vivo." Em ciência, in vivo refere-se à experimentação feita dentro ou no tecido vivo de um organismo vivo, em oposição a um parcialmente ou totalmente [morto. Experiências com animais e ensaios clínicos são formas de investigação in vivo. A análise in vivo é importante para o estudo de fenômenos dinâmicos e para estudos que exigem que as células mantenham suas atividades vitais. Por isso, na análise in vivo a observação é feita imediatamente após a coleta, conservando-se todas as características vitais do objeto de estudo.aracterísticas vitais do objeto de estudo.
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In vivo為拉丁文「在活體內」之意。在科學文献中，in vivo常指進行於完整且存活的個體內的組織的實驗，以区别在生物体上移除下来的組織或死亡的组织上进行的实验（对应的拉丁文為in vitro）。
, 생체내 또는 인 비보(라틴어: In vivo, "세포 안에서")는 살아 있는 세포 안에서 직접 생화학, 생물학 실험 등을 하는 것을 일컫는다.
, في الجسم الحي أو في الوسط الحيوي (باللاتين … في الجسم الحي أو في الوسط الحيوي (باللاتينية: in vivo) يطلق هذا المصطلح على العمليات والتفاعلات الحيوية وأحيانا التعديلات التي تحدث على الكائن الحي إما في بيئته أو داخل جسمه. فعلى سبيل المثال إذا كان النبات ينمو في بيئته الطبيعية في التربة بنفس الظروف يكون ناميًا في الحيوية، أما إذا كان ينمو في المعمل أو في المصانع في بيئة صناعية وظروف مشابهة لظروفه الطبيعية فهو ينمو صناعيًا «في المختبر» in vitro.ية فهو ينمو صناعيًا «في المختبر» in vitro.
, Als in vivo (lateinisch für ‚im Lebendigen … Als in vivo (lateinisch für ‚im Lebendigen‘) bezeichnet man in der Wissenschaft Prozesse, die im lebendigen Organismus ablaufen. Im Gegensatz dazu werden Abläufe, die in künstlicher Umgebung (z. B. im Reagenzglas) oder ganz allgemein außerhalb lebender Organismen stattfinden, mit dem Begriff in vitro belegt. Man sagt also beispielsweise, dass eine biochemische Reaktion entweder in vivo oder in vitro abläuft.on entweder in vivo oder in vitro abläuft.
, In vivo syftar på biologiska processer i l … In vivo syftar på biologiska processer i levande celler och vävnader när de befinner sig på sin naturliga plats i hela organismer, särskilt om processer som används i vetenskapliga försök och kliniska tester. Ett vanligt begrepp inom den gentekniska grenen genterapi. In vivo-forskning på människor följer Helsingforsdeklarationen och måste i Sverige godkännas av etikprövningsmyndigheten.ige godkännas av etikprövningsmyndigheten.
, in vivo（イン・ビボ）とは、「生体内で」を意味する用語であり、学術論文などにもしばしば登場する。由来はラテン語。
, In vivo (Latín: dentro de lo vivo) signifi … In vivo (Latín: dentro de lo vivo) significa "que ocurre o tiene lugar dentro de un organismo". En ciencia, in vivo se refiere a experimentación hecha dentro o en el tejido vivo de un organismo vivo, por oposición a uno parcial o muerto (denominado in vitro). Pruebas con animales y los ensayos clínicos son formas de investigación in vivo.nicos son formas de investigación in vivo.
, In vivo és una expressió llatina que s'utilitza per descriure experiments químics, físics o farmacològics que tenen lloc dins d'un organisme viu, per oposició als que es duen a terme en un ambient artificial (in vitro).
, Studies that are in vivo (Latin for "withi … Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism. This is not to be confused with experiments done in vitro ("within the glass"), i.e., in a laboratory environment using test tubes, Petri dishes, etc. Examples of investigations in vivo include: the pathogenesis of disease by comparing the effects of bacterial infection with the effects of purified bacterial toxins; the development of non-antibiotics, antiviral drugs, and new drugs generally; and new surgical procedures. Consequently, animal testing and clinical trials are major elements of in vivo ical trials are major elements of in vivo
, In vivo (em latim: dentro do vivo) signifi … In vivo (em latim: dentro do vivo) significa "que ocorre ou tem lugar dentro de um organismo ou em tecido vivo." Em ciência, in vivo refere-se à experimentação feita dentro ou no tecido vivo de um organismo vivo, em oposição a um parcialmente ou totalmente [morto. Experiências com animais e ensaios clínicos são formas de investigação in vivo.ínicos são formas de investigação in vivo.
, In vivo (en latin : « au sein du vivant ») … In vivo (en latin : « au sein du vivant ») est une expression latine qualifiant des recherches ou des examens pratiqués sur un organisme vivant, par opposition à in vitro ou ex vivo. Les essais cliniques sont une forme de recherche in vivo, en l'occurrence sur des humains. in vivo, en l'occurrence sur des humains.
, Η λατινογενής έκφραση in vivo, (που ελληνι … Η λατινογενής έκφραση in vivo, (που ελληνικά αποδίδεται «ἐν ζωῄ») αναφέρεται σε ότι λαμβάνει χώρα μέσα σε έναν έμβιο οργανισμό. Ιδιαίτερα στη Βιολογία ο όρος αναφέρεται σε πειράματα που πραγματοποιούνται σε ιστούς εντός ζώντος οργανισμού σε αντιδιαστολή με τον όρο in vitro (= «σε δοκιμαστικό σωλήνα»), που αναφέρεται σε αντίστοιχα πειράματα αποσπασμένων μερών εκτός του ζωντανού οργανισμού, καθώς και σε έρευνες και πειράματα ex vivo.
* Γενικά οι κλινικές δοκιμές και τα πειράματα με ζώα είναι μορφές έρευνας in vivo.άματα με ζώα είναι μορφές έρευνας in vivo.
, In vivo — у перекладі з латині: у живому ( … In vivo — у перекладі з латині: у живому (чи на живому) — означає, що подія відбувається всередині організму. У науці in vivo означає експерименти, що проводяться на живих тканинах і цілих організмах чи всередині них. Прикладами експериментів in vivo можуть бути експерименти на лабораторних тваринах чи клінічні випробовування.орних тваринах чи клінічні випробовування.
, In vivo (в буквальном переводе с лат. — «в … In vivo (в буквальном переводе с лат. — «в (на) живом»), то есть «внутри живого организма» или «внутри клетки». В науке in vivo обозначает проведение экспериментов на (или внутри) живой ткани при живом организме. Такое использование термина исключает использование части живого организма (так, как это делается при тестах in vitro) или использование мёртвого организма. Тестирование на животных и клинические испытания являются формами исследования in vivo.ния являются формами исследования in vivo.
, in vivo (en-organisma) (el la latina en vi … in vivo (en-organisma) (el la latina en vivulo) estas latin-devena scienca faktermino uzata por tiuj procezoj, kiuj okazas en vivanta organismo. Oni nomas tiun procezon, kiu okaza male, en artefarita medio (ekz. en ), - tio estas tute ekster la vivanta organismo - in vitro (ekster-organisma). Oni povas diri, ke iu biokemia reago okazas aŭ in vivo aŭ in vitro. Ĉar rezultoj de la ekster-organismaj eksperimentoj ne ĉiam respegulas la kondiĉojn de la en-organismaj eksperimentoj, tiel oni devas kontroli tiujn per en-organismaj eksperimentoj.oli tiujn per en-organismaj eksperimentoj.
, In vivo je latinský termín (in v, vivus ži … In vivo je latinský termín (in v, vivus živý) užívaný v biologii a medicíně. Znamená doslovně „v živém“, míněno:
* v živém organismu, lidském nebo zvířecím; může se týkat jak pokusu, tak skutečného průběhu určitého děje nebo nemoci;
* za života organismu, např. studium biologických pochodů za života organismu;
* v přirozených podmínkách, např. pozorování organismů (příp. jejich orgánů, ještě jednodušších biologických složek a látek) v přirozeném prostředí. Označení in vivo je antonymem k in vitro (pozorování v umělých, např. laboratorních podmínkách). umělých, např. laboratorních podmínkách).
, La locuzione latina in vivo, tradotta lett … La locuzione latina in vivo, tradotta letteralmente, significa nel vivente. La locuzione è usata per indicare fenomeni biologici riprodotti in un organismo vivente e non in provetta.Al contrario, se il fenomeno biologico si riproduce in provetta, si dice "in vitro", mentre se si riproduce in una simulazione matematica al computer si dice "in silico". In poche parole, il termine in vivo viene usato per cellule "vive", facenti parte di un organismo vivente; mentre il termine "in vitro" viene utilizzato per cellule di una coltura in laboratorio.per cellule di una coltura in laboratorio.
, In vivo (Latijn: binnen (in het) leven) is een proces dat in het complete levende lichaam van een organisme plaatsvindt. Verwante termen zijn in vitro (in glas) voor reageerbuistechnieken en in silico (in silicium) voor computersimulaties.
, In vivo (łac. „na żywym”) – termin stosowany zazwyczaj przy opisywaniu badań biologicznych, odnosi się do czegoś, co ma miejsce wewnątrz żywego organizmu – w ustroju żywym.
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In vivo
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, في الجسم الحي
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