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Death regulator Nedd2-like caspase (Nc, Ne … Death regulator Nedd2-like caspase (Nc, Nedd2-like caspase or Dronc) was firstly identified and characterised in Drosophila in 1999 as a cysteine protease containing an amino-terminal caspase recruitment domain. At first, it was thought of as an effector caspase involved in apoptosis, but subsequent findings have proved that it is, in fact, an initiator caspase with a crucial role in said type of programmed cell death.ole in said type of programmed cell death.
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Nc, Nedd2-like caspase, caspase-9
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Animation of the crystal structure of the Dronc caspase zymogen.
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3.0
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K20009
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Death regulator Nedd2-like caspase
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Drosophila melanogaster
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2
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CG8091
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Q9XYF4
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| rdfs:comment |
Death regulator Nedd2-like caspase (Nc, Ne … Death regulator Nedd2-like caspase (Nc, Nedd2-like caspase or Dronc) was firstly identified and characterised in Drosophila in 1999 as a cysteine protease containing an amino-terminal caspase recruitment domain. At first, it was thought of as an effector caspase involved in apoptosis, but subsequent findings have proved that it is, in fact, an initiator caspase with a crucial role in said type of programmed cell death.ole in said type of programmed cell death.
|
| rdfs:label |
Death regulator Nedd2-like caspase
|
