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Thomas Peter Maniatis, plus couramment Tom Maniatis, né le 8 mai 1943 à Denver (Colorado), est un biologiste américain, professeur de biologie moléculaire et cellulaire. Il est l'un des fondateurs de clonage moléculaire moderne.
, То́мас «Том» Маниа́тис (греч. Θωμάς «Τομ» … То́мас «Том» Маниа́тис (греч. Θωμάς «Τομ» Μανιάτης, англ. Thomas «Tom» Maniatis; род. 8 мая 1943, Денвер, Колорадо, США) — греко-американский учёный-биолог, специалист в области молекулярной биологии, цитологии и биохимии, один из самых цитируемых в мире греческих учёных. Первым в мире изолировал и клонировал ген человека, и использовал его для поиска мутаций, вызывающих болезнь. Способствовал формированию биофармацевтической индустрии, учредив совместно с Марком Ташне компанию «» — одну из первых в своём роде. Научный директор и CEO . Будучи профессором Колумбийского университета, является главой департамента биохимии и молекулярной биофизики , руководителем программы «Precision Medicine Initiative» и научно-исследовательской лаборатории «Maniatis Laboratory». Член Национальной академии наук США, Американской академии искусств и наук (1985), США и Американской ассоциации содействия развитию науки. Имеет h-индекс равный 149 и был процитирован 330 060 раз. Будучи одним из ведущих мировых экспертов в области механизмов генной регуляции, получил признание международного научного сообщества за внедрение инициативы по развитию технологии клонирования генов и её применению как при фундаментальных исследованиях, так и в биотехнологии, а также за исследования рекомбинантных ДНК. используемого во всём мире популярного лабораторного руководства «Методы генетической инженерии. Молекулярное клонирование» (англ. Molecular Cloning: A Laboratory Manual), называемого «библией» по молекулярному клонированию. Преподавал в Гарвардском университете, Лаборатории в Колд-Спринг-Харбор и Калифорнийском технологическом институте. Лауреат престижной Премии Ласкера-Кошланда за особые достижения в медицинской науке (2012).бые достижения в медицинской науке (2012).
, Tom Maniatis (eigentlich Thomas Peter Maniatis; * 8. Mai 1943 in Denver, Colorado) ist ein US-amerikanischer Molekularbiologe an der Columbia University in New York City.
, Tom Maniatis (born May 8, 1943), is an American professor of molecular and cellular biology. He is a professor at Columbia University, and serves as the Scientific Director and CEO of the New York Genome Center.
, Tom Maniatis (Denver, 8 maggio 1943) è un … Tom Maniatis (Denver, 8 maggio 1943) è un biologo statunitense, di origini greche. Professore di biologia molecolare e cellulare, Maniatis si è laureato presso la . All'età di 28 anni ha conseguito il Dottorato di Ricerca in Biologia Molecolare all'Università di Vanderbilt. Maniatis ha effettuato gli studi postdottorato con il professore Mark Ptashne presso la Università di Harvard e con il dottor Frederick Sanger presso il Medical Research Council Laboratorio di Biologia molecolare a Cambridge in Inghilterra. Maniatis ha ricoperto incarichi importanti presso la Harvard University, il Cold Spring Harbor Laboratory e il California Institute of Technology. Tom Maniatis ha lavorato in prima linea nei campi della biologia molecolare e cellulare in tutta la sua carriera. Ha determinato la sequenza nucleotidica di uno degli elementi di regolazione lambda mentre lavorava nel laboratorio di Frederick Sanger ed ha anche perfezionato protocolli per identificare e isolare i geni. Maniatis ha anche il merito di essere un pioniere nello sviluppo delle tecniche di clonaggio. Nel 1982 Maniatis insieme a Joe Sambrook e Edward Fritsch ha scritto "Molecular Cloning-A Laboratory Manual" ("La clonazione molecolare - Un manuale di laboratorio"), che ha avuto un enorme impatto sulle scienze della vita. Maniatis ha ricevuto numerosi premi tra cui nel 1981 l'Eli Lilly Research Award nel campo della microbiologia e immunologia dalla American Society for Microbiology. Maniatis è stato eletto membro della National Academy of Sciences nel 1985. Maniatis è anche un pioniere nel settore delle biotecnologie, avendo cofondato il Genetics Institute nel 1980, la ProScript Pharma nel 1994 e la Acceleron Pharma nel 2004. La ricerca attuale di Maniatis è rivolta ai meccanismi di regolazione genica nella immunità innata e nel cervello. Recentemente, il suo laboratorio ha avviato studi sulla sclerosi laterale amiotrofica (SLA). Maniatis attribuisce alle sue radici ellenica il buon lavoro svolto finora. "Quello che mi piace della Grecia", egli dice, "è il calore e la simpatia della gente e il fatto che le città così come il paesaggio siano così belle." così come il paesaggio siano così belle."
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То́мас «Том» Маниа́тис (греч. Θωμάς «Τομ» … То́мас «Том» Маниа́тис (греч. Θωμάς «Τομ» Μανιάτης, англ. Thomas «Tom» Maniatis; род. 8 мая 1943, Денвер, Колорадо, США) — греко-американский учёный-биолог, специалист в области молекулярной биологии, цитологии и биохимии, один из самых цитируемых в мире греческих учёных. Первым в мире изолировал и клонировал ген человека, и использовал его для поиска мутаций, вызывающих болезнь. Способствовал формированию биофармацевтической индустрии, учредив совместно с Марком Ташне компанию «» — одну из первых в своём роде. Научный директор и CEO . Имеет h-индекс равный 149 и был процитирован 330 060 раз.равный 149 и был процитирован 330 060 раз.
, Tom Maniatis (born May 8, 1943), is an American professor of molecular and cellular biology. He is a professor at Columbia University, and serves as the Scientific Director and CEO of the New York Genome Center.
, Thomas Peter Maniatis, plus couramment Tom Maniatis, né le 8 mai 1943 à Denver (Colorado), est un biologiste américain, professeur de biologie moléculaire et cellulaire. Il est l'un des fondateurs de clonage moléculaire moderne.
, Tom Maniatis (Denver, 8 maggio 1943) è un … Tom Maniatis (Denver, 8 maggio 1943) è un biologo statunitense, di origini greche. Professore di biologia molecolare e cellulare, Maniatis si è laureato presso la . All'età di 28 anni ha conseguito il Dottorato di Ricerca in Biologia Molecolare all'Università di Vanderbilt. Maniatis ha effettuato gli studi postdottorato con il professore Mark Ptashne presso la Università di Harvard e con il dottor Frederick Sanger presso il Medical Research Council Laboratorio di Biologia molecolare a Cambridge in Inghilterra. Maniatis ha ricoperto incarichi importanti presso la Harvard University, il Cold Spring Harbor Laboratory e il California Institute of Technology.y e il California Institute of Technology.
, Tom Maniatis (eigentlich Thomas Peter Maniatis; * 8. Mai 1943 in Denver, Colorado) ist ein US-amerikanischer Molekularbiologe an der Columbia University in New York City.
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Thomas Maniatis
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