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El sistema de defensa antimicrobiana del t … El sistema de defensa antimicrobiana del tracto respiratorio es un mecanismo de defensa en capas que se basa en componentes del sistema inmunitario innato y adaptativo para proteger los pulmones y el resto del tracto respiratorio contra los microorganismos inhalados. En la primera línea de defensa, las bacterias inhaladas quedan atrapadas por el moco y son arrastradas hacia la faringe y son tragadas. Las bacterias que penetran en la capa mucosa se tratan con una segunda línea de defensa que incluye péptidos antimicrobianos que son secretados por el epitelio superficial del tracto respiratorio que mata muchas cepas de bacterias. Esas bacterias que son resistentes a los péptidos antimicrobianos son destruidas por una variedad de especies reactivas de oxígeno producidas por los fagocitos. En una tercera línea de defensa y como último recurso, las infecciones bacterianas persistentes que escapan del sistema inmune innato son eliminadas por el sistema inmune adaptativo.iminadas por el sistema inmune adaptativo.
, The respiratory tract antimicrobial defens … The respiratory tract antimicrobial defense system is a layered defense mechanism which relies on components of both the innate and adaptive immune systems to protect the lungs and the rest of the respiratory tract against inhaled microorganisms. In the first line of defense, inhaled bacteria are trapped by mucus and are swept toward the pharynx and are swallowed. Bacteria which penetrate the mucous layer are dealt with a second line of defense which includes antimicrobial peptides that are secreted by the surface epithelium of the respiratory tract which kill many strains of bacteria. Those bacteria that are resistant to antimicrobial peptides are killed by a variety of reactive oxygen species produced by phagocytes. In a third line of defense and as a last resort, persistent bacterial infections which escape the innate immune system are eliminated by the adaptive immune system. eliminated by the adaptive immune system.
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El sistema de defensa antimicrobiana del t … El sistema de defensa antimicrobiana del tracto respiratorio es un mecanismo de defensa en capas que se basa en componentes del sistema inmunitario innato y adaptativo para proteger los pulmones y el resto del tracto respiratorio contra los microorganismos inhalados.orio contra los microorganismos inhalados.
, The respiratory tract antimicrobial defense system is a layered defense mechanism which relies on components of both the innate and adaptive immune systems to protect the lungs and the rest of the respiratory tract against inhaled microorganisms.
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rdfs:label |
Sistema de defensa antimicrobiana del tracto respiratorio
, Respiratory tract antimicrobial defense system
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