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H1299, also known as NCI-H1299 or CRL-5803 … H1299, also known as NCI-H1299 or CRL-5803, is a human non-small cell lung carcinoma cell line derived from the lymph node, which is widely used in research. As with other immortalized cell lines, H1299 cells can divide indefinitely. These cells have a homozygous partial deletion of the TP53 gene and as a result, do not express the tumor suppressor p53 protein which in part accounts for their proliferative propensity. These cells have also been reported to secrete the peptide hormone neuromedin B (NMB), but not gastrin releasing peptide (GRP)., but not gastrin releasing peptide (GRP).
, H1299 (也稱為NCI-H1299、CRL-5803) 是源自淋巴結的人類細胞系,在研究中得到廣泛應用。H1299細胞與其他永生細胞系一樣可以無限期分裂,並且因p53基因的純合子部分缺失,故而不表達腫瘤抑制基因p53蛋白,說明了它們的增殖傾向。有研究指出這些細胞會分泌,但是不會分泌。
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rdfs:comment |
H1299, also known as NCI-H1299 or CRL-5803 … H1299, also known as NCI-H1299 or CRL-5803, is a human non-small cell lung carcinoma cell line derived from the lymph node, which is widely used in research. As with other immortalized cell lines, H1299 cells can divide indefinitely. These cells have a homozygous partial deletion of the TP53 gene and as a result, do not express the tumor suppressor p53 protein which in part accounts for their proliferative propensity. These cells have also been reported to secrete the peptide hormone neuromedin B (NMB), but not gastrin releasing peptide (GRP)., but not gastrin releasing peptide (GRP).
, H1299 (也稱為NCI-H1299、CRL-5803) 是源自淋巴結的人類細胞系,在研究中得到廣泛應用。H1299細胞與其他永生細胞系一樣可以無限期分裂,並且因p53基因的純合子部分缺失,故而不表達腫瘤抑制基因p53蛋白,說明了它們的增殖傾向。有研究指出這些細胞會分泌,但是不會分泌。
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rdfs:label |
H1299
, H1299細胞
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