| http://dbpedia.org/ontology/abstract
|
Fosdenopterin (or cyclic pyranopterin mono … Fosdenopterin (or cyclic pyranopterin monophosphate, cPMP), sold under the brand name Nulibry, is a medication used to reduce the risk of death due to a rare genetic disease known as molybdenum cofactor deficiency type A. The most common side effects include complications related to the intravenous line, fever, respiratory infections, vomiting, gastroenteritis, and diarrhea. Fosdenopterin was approved for medical use in the United States in February 2021, It is the first medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of molybdenum cofactor deficiency type A. and in the European Union in September 2022.d in the European Union in September 2022.
, Fosdenopterina (DCI) ou piranopterina cícl … Fosdenopterina (DCI) ou piranopterina cíclica monofosfato (em inglês: Cyclic pyranopterin monophosphate, cPMP) é um fármaco experimental, utilizado no tratamento de deficiência do cofator de molibdênio. Foi utilizado pela primeira vez em uma bebê australiana denominada Baby Z. A droga foi desenvolvida pela Universidade de Colônia, na Alemanha e testada poucas vezes apenas em ratos, sendo o tratamento de Baby Z autorizado por um comitê de ética. Este medicamento reduziu os índices de sulfito, substância tóxica que causa degeneração do cérebro relacionada com a deficiência do cofator de molibdênio.om a deficiência do cofator de molibdênio.
, Fosdenopterin ist der internationale Freiname für das cyclische Pyranopterinmonophosphat (cPMP). Als Nulibry ist es in den USA und in der EU zur Behandlung des Molybdän-Cofaktor-Mangels vom Typ A (MoCD-A) zugelassen.
|
| http://dbpedia.org/ontology/alternativeName
|
Nulibry
|
| http://dbpedia.org/ontology/casNumber
|
150829-29-1
|
| http://dbpedia.org/ontology/chEMBL
|
2338675
|
| http://dbpedia.org/ontology/drugbank
|
DB16628
|
| http://dbpedia.org/ontology/fdaUniiCode
|
4X7K2681Y7
|
| http://dbpedia.org/ontology/kegg
|
D11779
|
| http://dbpedia.org/ontology/pubchem
|
135894389
|
| http://dbpedia.org/ontology/thumbnail
|
http://commons.wikimedia.org/wiki/Special:FilePath/Cyclic_pyranopterin_monophosphate.svg?width=300 +
|
| http://dbpedia.org/ontology/wikiPageExternalLink
|
https://druginfo.nlm.nih.gov/drugportal/name/fosdenopterin +
|
| http://dbpedia.org/ontology/wikiPageID
|
66925042
|
| http://dbpedia.org/ontology/wikiPageLength
|
11427
|
| http://dbpedia.org/ontology/wikiPageRevisionID
|
1116106940
|
| http://dbpedia.org/ontology/wikiPageWikiLink
|
http://dbpedia.org/resource/Intravenous_therapy +
, http://dbpedia.org/resource/Xanthine_dehydrogenase +
, http://dbpedia.org/resource/Indication_%28medicine%29 +
, http://dbpedia.org/resource/Gastroenteritis +
, http://dbpedia.org/resource/Food_and_Drug_Administration +
, http://dbpedia.org/resource/Orphan_drug +
, http://dbpedia.org/resource/Priority_review +
, http://dbpedia.org/resource/Category:Organophosphates +
, http://dbpedia.org/resource/Aldehyde_oxidase +
, http://dbpedia.org/resource/Respiratory_tract_infection +
, http://dbpedia.org/resource/Molybdenum_cofactor_deficiency +
, http://dbpedia.org/resource/European_Medicines_Agency +
, http://dbpedia.org/resource/Breakthrough_therapy +
, http://dbpedia.org/resource/Xanthine_oxidase +
, http://dbpedia.org/resource/Category:Orphan_drugs +
, http://dbpedia.org/resource/Sulfite_oxidase +
, http://dbpedia.org/resource/Molybdopterin +
, http://dbpedia.org/resource/Committee_for_Medicinal_Products_for_Human_Use +
, http://dbpedia.org/resource/Medication +
, http://dbpedia.org/resource/University_of_Cologne +
, http://dbpedia.org/resource/Braunschweig_University_of_Technology +
, http://dbpedia.org/resource/Intravenous +
, http://dbpedia.org/resource/Category:Breakthrough_therapy +
, http://dbpedia.org/resource/Diarrhea +
|
| http://dbpedia.org/property/atcPrefix
|
A16
|
| http://dbpedia.org/property/atcSuffix
|
AX19
|
| http://dbpedia.org/property/c
|
10
|
| http://dbpedia.org/property/casNumber
|
150829
|
| http://dbpedia.org/property/chembl
|
2338675
|
| http://dbpedia.org/property/chemspiderid
|
17221217
|
| http://dbpedia.org/property/dailymedid
|
Fosdenopterin
|
| http://dbpedia.org/property/drugbank
|
DB16628
|
| http://dbpedia.org/property/h
|
14
|
| http://dbpedia.org/property/iupacName
|
5
|
| http://dbpedia.org/property/kegg
|
D11779
|
| http://dbpedia.org/property/legalEu
|
Rx-only
|
| http://dbpedia.org/property/legalUs
|
Rx-only
|
| http://dbpedia.org/property/n
|
5
|
| http://dbpedia.org/property/o
|
8
|
| http://dbpedia.org/property/p
|
1
|
| http://dbpedia.org/property/pubchem
|
135894389
|
| http://dbpedia.org/property/routesOfAdministration
|
http://dbpedia.org/resource/Intravenous +
|
| http://dbpedia.org/property/smiles
|
NC1=NCC2=CN1
|
| http://dbpedia.org/property/stdinchi
|
1
|
| http://dbpedia.org/property/stdinchikey
|
CZAKJJUNKNPTTO-AJFJRRQVSA-N
|
| http://dbpedia.org/property/synonyms
|
Precursor Z, ALXN1101
|
| http://dbpedia.org/property/tradename
|
Nulibry
|
| http://dbpedia.org/property/unii
|
4
|
| http://dbpedia.org/property/wikiPageUsesTemplate
|
http://dbpedia.org/resource/Template:Reflist +
, http://dbpedia.org/resource/Template:Cite_web +
, http://dbpedia.org/resource/Template:Use_American_English +
, http://dbpedia.org/resource/Template:Use_dmy_dates +
, http://dbpedia.org/resource/Template:Portal_bar +
, http://dbpedia.org/resource/Template:Infobox_drug +
, http://dbpedia.org/resource/Template:Short_description +
|
| http://purl.org/dc/terms/subject
|
http://dbpedia.org/resource/Category:Orphan_drugs +
, http://dbpedia.org/resource/Category:Breakthrough_therapy +
, http://dbpedia.org/resource/Category:Organophosphates +
|
| http://www.w3.org/ns/prov#wasDerivedFrom
|
http://en.wikipedia.org/wiki/Fosdenopterin?oldid=1116106940&ns=0 +
|
| http://xmlns.com/foaf/0.1/depiction
|
http://commons.wikimedia.org/wiki/Special:FilePath/Cyclic_pyranopterin_monophosphate.svg +
|
| http://xmlns.com/foaf/0.1/isPrimaryTopicOf
|
http://en.wikipedia.org/wiki/Fosdenopterin +
|
| owl:sameAs |
https://global.dbpedia.org/id/4ihkz +
, http://dbpedia.org/resource/Fosdenopterin +
, http://uz.dbpedia.org/resource/Fosdenopterin +
, http://de.dbpedia.org/resource/Fosdenopterin +
, http://sh.dbpedia.org/resource/Cikli%C4%8Dni_piranopterinski_monofosfat +
, http://www.wikidata.org/entity/Q5198226 +
, http://sr.dbpedia.org/resource/Cikli%C4%8Dni_piranopterinski_monofosfat +
, http://pt.dbpedia.org/resource/Fosdenopterina +
|
| rdf:type |
http://dbpedia.org/ontology/ChemicalSubstance +
, http://www.wikidata.org/entity/Q8386 +
, http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#ChemicalObject +
, http://dbpedia.org/ontology/Drug +
|
| rdfs:comment |
Fosdenopterina (DCI) ou piranopterina cícl … Fosdenopterina (DCI) ou piranopterina cíclica monofosfato (em inglês: Cyclic pyranopterin monophosphate, cPMP) é um fármaco experimental, utilizado no tratamento de deficiência do cofator de molibdênio. Foi utilizado pela primeira vez em uma bebê australiana denominada Baby Z. A droga foi desenvolvida pela Universidade de Colônia, na Alemanha e testada poucas vezes apenas em ratos, sendo o tratamento de Baby Z autorizado por um comitê de ética. Baby Z autorizado por um comitê de ética.
, Fosdenopterin (or cyclic pyranopterin mono … Fosdenopterin (or cyclic pyranopterin monophosphate, cPMP), sold under the brand name Nulibry, is a medication used to reduce the risk of death due to a rare genetic disease known as molybdenum cofactor deficiency type A. The most common side effects include complications related to the intravenous line, fever, respiratory infections, vomiting, gastroenteritis, and diarrhea., vomiting, gastroenteritis, and diarrhea.
, Fosdenopterin ist der internationale Freiname für das cyclische Pyranopterinmonophosphat (cPMP). Als Nulibry ist es in den USA und in der EU zur Behandlung des Molybdän-Cofaktor-Mangels vom Typ A (MoCD-A) zugelassen.
|
| rdfs:label |
Fosdenopterina
, Fosdenopterin
|
