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Cellulose acetate phthalate (CAP), also kn … Cellulose acetate phthalate (CAP), also known as cellacefate (INN) and cellulosi acetas phthalas, is a commonly used polymer phthalate in the formulation of pharmaceuticals, such as the enteric coating of tablets or capsules and for controlled release formulations. It is a cellulose polymer where about half of the hydroxyls are esterified with acetyls, a quarter are esterified with one or two carboxyls of a phthalic acid, and the remainder are unchanged. It is a hygroscopic white to off-white free-flowing powder, granules, or flakes. It is tasteless and odorless, though may have a weak odor of acetic acid. Its main use in pharmaceutics is with enteric formulations. It can be used together with other coating agents, e.g. ethyl cellulose. Cellulose acetate phthalate is commonly plasticized with diethyl phthalate, a hydrophobic compound, or triethyl citrate, a hydrophilic compound; other compatible plasticizers are various phthalates, triacetin, dibutyl tartrate, glycerol, propylene glycol, , , acetylated monoglycerides, etc.lycol, , , acetylated monoglycerides, etc.
, فثالات أسيتات السليولوز هو مشتق عضوي سليولوز تستبدل فيه حوالي النصف من مجموعات الهيدروكسيل بمجموعات من الأسيتيل، وحوالي الربع بمجموعات من الفثالات.
, Celluloseacetatphthalat ist ein Biopolymer … Celluloseacetatphthalat ist ein Biopolymer, das auf Cellulose basiert. Es ist wie Celluloseacetat, Cellulosepropionat, Celluloseacetatpropionat und Celluloseacetatbutyrat ein Ester der Cellulose mit Carbonsäuren. Während bei Celluloseacetat die Veresterung nur durch Essigsäure erfolgte, sind im Celluloseacetatphthalat in Pharmaqualität statistisch 21,5 bis 26,0 % der Hydroxygruppen der Cellulose durch Essigsäure und 30,0 bis 36,0 % durch Phthalsäure verestert. Celluloseacetatphthalat enthält also Acetylgruppen (C2H3O) und (C8H5O3).t also Acetylgruppen (C2H3O) und (C8H5O3).
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Cellacefate
, CAP
, Cellulosi acetas phthalas
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Cellulose, acetate, 1,2-benzenedicarboxylate
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Cellulosi acetas phthalas
, CAP
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Cellulose, acetate, 1,2-benzenedicarboxylate
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| rdfs:comment |
Celluloseacetatphthalat ist ein Biopolymer … Celluloseacetatphthalat ist ein Biopolymer, das auf Cellulose basiert. Es ist wie Celluloseacetat, Cellulosepropionat, Celluloseacetatpropionat und Celluloseacetatbutyrat ein Ester der Cellulose mit Carbonsäuren. Während bei Celluloseacetat die Veresterung nur durch Essigsäure erfolgte, sind im Celluloseacetatphthalat in Pharmaqualität statistisch 21,5 bis 26,0 % der Hydroxygruppen der Cellulose durch Essigsäure und 30,0 bis 36,0 % durch Phthalsäure verestert. Celluloseacetatphthalat enthält also Acetylgruppen (C2H3O) und (C8H5O3).t also Acetylgruppen (C2H3O) und (C8H5O3).
, Cellulose acetate phthalate (CAP), also kn … Cellulose acetate phthalate (CAP), also known as cellacefate (INN) and cellulosi acetas phthalas, is a commonly used polymer phthalate in the formulation of pharmaceuticals, such as the enteric coating of tablets or capsules and for controlled release formulations. It is a cellulose polymer where about half of the hydroxyls are esterified with acetyls, a quarter are esterified with one or two carboxyls of a phthalic acid, and the remainder are unchanged. It is a hygroscopic white to off-white free-flowing powder, granules, or flakes. It is tasteless and odorless, though may have a weak odor of acetic acid. Its main use in pharmaceutics is with enteric formulations. It can be used together with other coating agents, e.g. ethyl cellulose. Cellulose acetate phthalate is commonly plasticized wcetate phthalate is commonly plasticized w
, فثالات أسيتات السليولوز هو مشتق عضوي سليولوز تستبدل فيه حوالي النصف من مجموعات الهيدروكسيل بمجموعات من الأسيتيل، وحوالي الربع بمجموعات من الفثالات.
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| rdfs:label |
Cellulose acetate phthalate
, فثالات أسيتات السليولوز
, Celluloseacetatphthalat
|
