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X-linked thrombocytopenia, also referred t … X-linked thrombocytopenia, also referred to as XLT or thrombocytopenia 1, is an inherited clotting disorder that primarily affects males. It is a WAS-related disorder, meaning it is caused by a mutation in the Wiskott–Aldrich syndrome (WAS) gene, which is located on the short arm of the X chromosome. WAS-related disorders include Wiskott–Aldrich syndrome, XLT, and X-linked congenital neutropenia (XLN). Of the WAS-related disorders, X-linked thrombocytopenia is considered to be the milder phenotype. Between 1 and 10 per million males worldwide are affected with this disorder. Females may be affected with this disorder but this is very rare since females have two X chromosomes and are therefore typically carriers of the mutation.refore typically carriers of the mutation.
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X-linked thrombocytopenia with normal platelets
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https://medlineplus.gov/genetics/condition/x-linked-thrombocytopenia/ +
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, https://www.ncbi.nlm.nih.gov/gtr/conditions/C1839163/ +
, https://www.ncbi.nlm.nih.gov/books/NBK1178/%23was.Management_1 +
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This condition is inherited in an X-linked recessive manner
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D69.4
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X-linked thrombocytopenia
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X-linked thrombocytopenia with normal platelets
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| rdfs:comment |
X-linked thrombocytopenia, also referred t … X-linked thrombocytopenia, also referred to as XLT or thrombocytopenia 1, is an inherited clotting disorder that primarily affects males. It is a WAS-related disorder, meaning it is caused by a mutation in the Wiskott–Aldrich syndrome (WAS) gene, which is located on the short arm of the X chromosome. WAS-related disorders include Wiskott–Aldrich syndrome, XLT, and X-linked congenital neutropenia (XLN). Of the WAS-related disorders, X-linked thrombocytopenia is considered to be the milder phenotype. Between 1 and 10 per million males worldwide are affected with this disorder. Females may be affected with this disorder but this is very rare since females have two X chromosomes and are therefore typically carriers of the mutation.refore typically carriers of the mutation.
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X-linked thrombocytopenia
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