| http://dbpedia.org/ontology/abstract
|
Tuberous sclerosis complex (TSC) tumor sup … Tuberous sclerosis complex (TSC) tumor suppressors form the TSC1-TSC2 molecular complex. Under poor growth conditions the TSC1-TSC2 complex limits cell growth. A key promoter of cell growth, mTORC1, is inhibited by the tuberous sclerosis complex. Insulin activates mTORC1 and causes dissociation of TSC from the surface of lysosomes. Resistance to ischemia-reperfusion injury by protein restriction is mediated by activation of the tuberous sclerosis complex.ivation of the tuberous sclerosis complex.
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| http://dbpedia.org/ontology/wikiPageID
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3705272
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|
2007
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|
| rdfs:comment |
Tuberous sclerosis complex (TSC) tumor sup … Tuberous sclerosis complex (TSC) tumor suppressors form the TSC1-TSC2 molecular complex. Under poor growth conditions the TSC1-TSC2 complex limits cell growth. A key promoter of cell growth, mTORC1, is inhibited by the tuberous sclerosis complex. Insulin activates mTORC1 and causes dissociation of TSC from the surface of lysosomes. Resistance to ischemia-reperfusion injury by protein restriction is mediated by activation of the tuberous sclerosis complex.ivation of the tuberous sclerosis complex.
|
| rdfs:label |
Tuberous sclerosis complex tumor suppressors
|
