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http://dbpedia.org/ontology/abstract In enzymology, a thiamine diphosphokinase In enzymology, a thiamine diphosphokinase (EC 2.7.6.2) is an enzyme that catalyzes the chemical reaction ATP + thiamine AMP + thiamine diphosphate Thus, the two substrates of this enzyme are ATP and thiamine, whereas its two products are AMP and thiamine diphosphate. This enzyme belongs to the family of transferases, specifically those transferring two phosphorus-containing groups (diphosphotransferases). The systematic name of this enzyme class is ATP:thiamine diphosphotransferase. Other names in common use include thiamin kinase, thiamine pyrophosphokinase, ATP:thiamin pyrophosphotransferase, thiamin pyrophosphokinase, thiamin pyrophosphotransferase, thiaminokinase, thiamin:ATP pyrophosphotransferase, and TPTase. This enzyme participates in thiamine metabolism.nzyme participates in thiamine metabolism. , Thiaminpyrophosphokinase (TPK) ist das EnzThiaminpyrophosphokinase (TPK) ist das Enzym, das die Umwandlung von Thiamin (Vitamin B1) in Thiaminpyrophosphat (TPP) katalysiert. Diese Phosphorylierung ist notwendig, da Thiamin selbst keine Verwendung im Stoffwechsel hat. TPK kommt in allen Eukaryoten vor, im Menschen ist es besonders in Herz, Nieren, Hoden, Dünndarm und Leukozyten lokalisiert. Varianten des Enzyms sind möglicherweise mit Unterschieden im Geburtsgewicht assoziiert. Die Regulation von TPK erfolgt über das Sp1 cis-Element. von TPK erfolgt über das Sp1 cis-Element. , Une thiamine diphosphokinase est une phospUne thiamine diphosphokinase est une phosphotransférase qui catalyse la réaction : ATP + thiamine AMP + TPP. Cette enzyme convertit la vitamine B1 en thiamine pyrophosphate, cofacteur indispensable à de nombreuses réactions clés du métabolisme. Elle est présente chez tous les eucaryotes ; chez l'homme, elle est particulièrement exprimée dans le cœur, les reins, les testicules, l'intestin grêle et les leucocytes.cules, l'intestin grêle et les leucocytes.
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rdfs:comment In enzymology, a thiamine diphosphokinase In enzymology, a thiamine diphosphokinase (EC 2.7.6.2) is an enzyme that catalyzes the chemical reaction ATP + thiamine AMP + thiamine diphosphate Thus, the two substrates of this enzyme are ATP and thiamine, whereas its two products are AMP and thiamine diphosphate.products are AMP and thiamine diphosphate. , Thiaminpyrophosphokinase (TPK) ist das EnzThiaminpyrophosphokinase (TPK) ist das Enzym, das die Umwandlung von Thiamin (Vitamin B1) in Thiaminpyrophosphat (TPP) katalysiert. Diese Phosphorylierung ist notwendig, da Thiamin selbst keine Verwendung im Stoffwechsel hat. TPK kommt in allen Eukaryoten vor, im Menschen ist es besonders in Herz, Nieren, Hoden, Dünndarm und Leukozyten lokalisiert. Varianten des Enzyms sind möglicherweise mit Unterschieden im Geburtsgewicht assoziiert. Die Regulation von TPK erfolgt über das Sp1 cis-Element. von TPK erfolgt über das Sp1 cis-Element. , Une thiamine diphosphokinase est une phospUne thiamine diphosphokinase est une phosphotransférase qui catalyse la réaction : ATP + thiamine AMP + TPP. Cette enzyme convertit la vitamine B1 en thiamine pyrophosphate, cofacteur indispensable à de nombreuses réactions clés du métabolisme. Elle est présente chez tous les eucaryotes ; chez l'homme, elle est particulièrement exprimée dans le cœur, les reins, les testicules, l'intestin grêle et les leucocytes.cules, l'intestin grêle et les leucocytes.
rdfs:label Thiamine diphosphokinase , Thiaminpyrophosphokinase
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