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Tezosentan ist ein potenzieller Arzneistof … Tezosentan ist ein potenzieller Arzneistoff aus der Gruppe der Endothelinrezeptor-Antagonisten, der von dem Schweizer Pharmaunternehmen Actelion entwickelt wurde. Er sollte zur Behandlung der akuten Herzinsuffizienz eingesetzt werden. Neuere Studien haben jedoch gezeigt, dass Tezosentan weder eine Dyspnoe verbessert noch das Risiko für kardiovaskuläre Ereignisse verringert.für kardiovaskuläre Ereignisse verringert.
, Tezosentan is a non-selective ETA and ETB … Tezosentan is a non-selective ETA and ETB receptor antagonist. It acts as a vasodilator and was designed by Actelion as a therapy for patients with acute heart failure. However, studies showed that tezosentan did not improve dyspnea or reduce the risk of fatal or nonfatal cardiovascular events.f fatal or nonfatal cardiovascular events.
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Space-filling model of the tezosentan molecule
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N-[6--5--2-[2-pyridin-4-yl]pyrimidin-4-yl]-5-propan-2-ylpyridine-2-sulfonamide
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| rdfs:comment |
Tezosentan is a non-selective ETA and ETB … Tezosentan is a non-selective ETA and ETB receptor antagonist. It acts as a vasodilator and was designed by Actelion as a therapy for patients with acute heart failure. However, studies showed that tezosentan did not improve dyspnea or reduce the risk of fatal or nonfatal cardiovascular events.f fatal or nonfatal cardiovascular events.
, Tezosentan ist ein potenzieller Arzneistof … Tezosentan ist ein potenzieller Arzneistoff aus der Gruppe der Endothelinrezeptor-Antagonisten, der von dem Schweizer Pharmaunternehmen Actelion entwickelt wurde. Er sollte zur Behandlung der akuten Herzinsuffizienz eingesetzt werden. Neuere Studien haben jedoch gezeigt, dass Tezosentan weder eine Dyspnoe verbessert noch das Risiko für kardiovaskuläre Ereignisse verringert.für kardiovaskuläre Ereignisse verringert.
|
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Tezosentan
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