| http://dbpedia.org/ontology/abstract
|
سونيديغيب (بالإنجليزية: Sonidegib) هو دواء يُستعمل في علاج:
* سرطان الخلايا القاعدية
, Sonidegib (INN), sold under the brand name Odomzo, is a medication used to treat cancer. Sonidegib is Hedgehog signaling pathway inhibitor (via smoothened antagonism).
|
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|
Odomzo
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|
956697-53-3
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90863
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| http://dbpedia.org/ontology/chEMBL
|
2105737
|
| http://dbpedia.org/ontology/class
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http://dbpedia.org/resource/Antineoplastic_agents +
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DB09143
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|
0RLU3VTK5M
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D10119
, D10729
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a615034
|
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24775005
|
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http://commons.wikimedia.org/wiki/Special:FilePath/Sonidegib.svg?width=300 +
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|
https://druginfo.nlm.nih.gov/drugportal/name/sonidegib +
, https://druginfo.nlm.nih.gov/drugportal/name/sonidegib%20phosphate +
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| http://dbpedia.org/ontology/wikiPageID
|
41957427
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|
13360
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|
1096075693
|
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http://dbpedia.org/resource/Category:Benzamides +
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| http://dbpedia.org/property/atcPrefix
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L01
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| http://dbpedia.org/property/atcSuffix
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XJ02
|
| http://dbpedia.org/property/bioavailability
|
<10%
|
| http://dbpedia.org/property/c
|
26
|
| http://dbpedia.org/property/casNumber
|
956697
|
| http://dbpedia.org/property/chebi
|
90863
|
| http://dbpedia.org/property/chembl
|
2105737
|
| http://dbpedia.org/property/chemspiderid
|
25027390
|
| http://dbpedia.org/property/class
|
http://dbpedia.org/resource/Antineoplastic_agents +
|
| http://dbpedia.org/property/dailymedid
|
Sonidegib
|
| http://dbpedia.org/property/drugbank
|
DB09143
|
| http://dbpedia.org/property/eliminationHalfLife
|
2419200.0
|
| http://dbpedia.org/property/excretion
|
Feces , urine
|
| http://dbpedia.org/property/f
|
3
|
| http://dbpedia.org/property/h
|
26
|
| http://dbpedia.org/property/index2Label
|
as salt
|
| http://dbpedia.org/property/iupacName
|
N-[6-[-2,6-Dimethylmorpholin-4-yl]pyridin-3-yl]-2-methyl-3-[4-phenyl]benzamide
|
| http://dbpedia.org/property/kegg
|
D10729
, D10119
|
| http://dbpedia.org/property/legalCa
|
Rx-only
|
| http://dbpedia.org/property/legalEu
|
Rx-only
|
| http://dbpedia.org/property/legalStatus
|
Rx-only
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| http://dbpedia.org/property/legalUs
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Rx-only
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|
yes
|
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a615034
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Liver
|
| http://dbpedia.org/property/n
|
3
|
| http://dbpedia.org/property/o
|
3
|
| http://dbpedia.org/property/pregnancyCategory
|
Contraindicated
|
| http://dbpedia.org/property/proteinBound
|
>97%
|
| http://dbpedia.org/property/pubchem
|
24775005
|
| http://dbpedia.org/property/routesOfAdministration
|
http://dbpedia.org/resource/Oral_administration +
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C[C@@H]1CNC2=NC=CNCC3=CC=CCC4=CC=COCF
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1
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| http://dbpedia.org/property/stdinchikey
|
VZZJRYRQSPEMTK-CALCHBBNSA-N
|
| http://dbpedia.org/property/synonyms
|
LDE225, erismodegib
|
| http://dbpedia.org/property/tradename
|
Odomzo
|
| http://dbpedia.org/property/unii
|
0
|
| http://dbpedia.org/property/width
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275
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http://dbpedia.org/resource/Template:Cascite +
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|
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http://dbpedia.org/resource/Category:Teratogens +
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, http://dbpedia.org/resource/Category:Novartis_brands +
, http://dbpedia.org/resource/Category:Trifluoromethyl_ethers +
|
| http://purl.org/linguistics/gold/hypernym
|
http://dbpedia.org/resource/Hedgehog +
|
| http://www.w3.org/ns/prov#wasDerivedFrom
|
http://en.wikipedia.org/wiki/Sonidegib?oldid=1096075693&ns=0 +
|
| http://xmlns.com/foaf/0.1/depiction
|
http://commons.wikimedia.org/wiki/Special:FilePath/Sonidegib.svg +
|
| http://xmlns.com/foaf/0.1/isPrimaryTopicOf
|
http://en.wikipedia.org/wiki/Sonidegib +
|
| owl:sameAs |
http://rdf.freebase.com/ns/m.0_s4_pg +
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, http://yago-knowledge.org/resource/Sonidegib +
, http://dbpedia.org/resource/Sonidegib +
, http://www.wikidata.org/entity/Q22075856 +
|
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http://dbpedia.org/class/yago/Drug103247620 +
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|
| rdfs:comment |
سونيديغيب (بالإنجليزية: Sonidegib) هو دواء يُستعمل في علاج:
* سرطان الخلايا القاعدية
, Sonidegib (INN), sold under the brand name Odomzo, is a medication used to treat cancer. Sonidegib is Hedgehog signaling pathway inhibitor (via smoothened antagonism).
|
| rdfs:label |
سونيديغيب
, Sonidegib
|
