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|
Setrobuvir (also known as ANA-598) was an … Setrobuvir (also known as ANA-598) was an experimental drug candidate for the treatment of hepatitis C that was discovered at Anadys Pharmaceuticals, which was acquired by Roche in 2011; Roche terminated development in July 2015. It was in Phase IIb clinical trials, used in combination with interferon and ribavirin, targeting hepatitis C patients with genotype 1. Setrobuvir works by inhibiting the hepatitis C enzyme NS5B, an RNA polymerase.epatitis C enzyme NS5B, an RNA polymerase.
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ANA-598; ANA598
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N-(3-{(4aR,5S,8R,8aS)-1-[(4-Fluorophenyl)methyl]-4-hydroxy-2-oxo-1,2,4a,5,6,7,8,8a-octahydro-5,8-methanoquinolin-3-yl}-1,1-dioxo-1,4-dihydro-1λ6,2,4-benzothiadiazin-7-yl)methanesulfonamide
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http://commons.wikimedia.org/wiki/Special:FilePath/Setrobuvir.svg?width=300 +
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33518991
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4670
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1113763467
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Setrobuvir.svg
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200
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ANA-598; ANA598
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| http://dbpedia.org/property/pin
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N-methanesulfonamide
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changed
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461749550
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http://commons.wikimedia.org/wiki/Special:FilePath/Setrobuvir.svg +
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http://en.wikipedia.org/wiki/Setrobuvir +
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|
| rdfs:comment |
Setrobuvir (also known as ANA-598) was an … Setrobuvir (also known as ANA-598) was an experimental drug candidate for the treatment of hepatitis C that was discovered at Anadys Pharmaceuticals, which was acquired by Roche in 2011; Roche terminated development in July 2015. It was in Phase IIb clinical trials, used in combination with interferon and ribavirin, targeting hepatitis C patients with genotype 1. Setrobuvir works by inhibiting the hepatitis C enzyme NS5B, an RNA polymerase.epatitis C enzyme NS5B, an RNA polymerase.
|
| rdfs:label |
Setrobuvir
|
