| http://dbpedia.org/ontology/abstract
|
The Rev-Erb proteins are members of the nu … The Rev-Erb proteins are members of the nuclear receptor (NR) superfamily of intracellular transcription factors and key regulatory components of the circadian clock. There are two forms of the receptor, Rev-Erb alpha and Rev-Erb beta, which are each encoded by a separate gene (NR1D1 and NR1D2, respectively). These proteins act as key regulators of clock gene expression through transcriptional repression of Bmal1. Through their regulation of clock-controlled genes, the Rev-Erb proteins affect several physiological processes throughout the body, including metabolic, endocrine, and immune pathways. In the NRNC classification scheme, Rev-Erb is nuclear receptor subfamily 1 group D (NR1D). The name "Rev-Erb" derived by truncation from "Rev-ERBA" (Rev-Erbα), which in turn was named because it was on the opposite strand of ERBA (THRA) oncogene. The paralogous Rev-Erbβ does not seem to have anything special on its reverse strand. Older sources may use "Rev-ERBA" as the family name.ces may use "Rev-ERBA" as the family name.
, Les protéines Rev-erb sont des protéines de la superfamille des récepteurs nucléaires. Elles sont notamment impliquées dans la régulation du cycle circadien
|
| http://dbpedia.org/ontology/arm
|
q
, p
|
| http://dbpedia.org/ontology/band
|
24.1
, 11.2
|
| http://dbpedia.org/ontology/chromosome
|
3
, 17
|
| http://dbpedia.org/ontology/entrezgene
|
9975
, 9572
|
| http://dbpedia.org/ontology/hgncid
|
7963
, 7962
|
| http://dbpedia.org/ontology/omim
|
602408
, 602304
|
| http://dbpedia.org/ontology/refseq
|
NM_021724
, XM_001130839
|
| http://dbpedia.org/ontology/symbol
|
BD73, RVR, EAR-1r, HZF2, Hs.37288
, NR1D2
, NR1D1
, ear-1, hRev, Rev-ErbAalpha, THRA1
|
| http://dbpedia.org/ontology/thumbnail
|
http://commons.wikimedia.org/wiki/Special:FilePath/Model_of_REV-ERB-mediated_Circadian_Gene_Expression.png?width=300 +
|
| http://dbpedia.org/ontology/uniprot
|
P20393
, Q14995
|
| http://dbpedia.org/ontology/wikiPageID
|
12132873
|
| http://dbpedia.org/ontology/wikiPageLength
|
4360
|
| http://dbpedia.org/ontology/wikiPageRevisionID
|
1103989609
|
| http://dbpedia.org/ontology/wikiPageWikiLink
|
http://dbpedia.org/resource/Nuclear_receptor +
, http://dbpedia.org/resource/Endocrine_system +
, http://dbpedia.org/resource/Circadian_clock +
, http://dbpedia.org/resource/File:Model_of_REV-ERB-mediated_Circadian_Gene_Expression.png +
, http://dbpedia.org/resource/BMAL1 +
, http://dbpedia.org/resource/Metabolism +
, http://dbpedia.org/resource/NR1D2 +
, http://dbpedia.org/resource/NR1D1 +
, http://dbpedia.org/resource/Rev-ErbA_beta +
, http://dbpedia.org/resource/Immune_system +
, http://dbpedia.org/resource/Transcription_factor +
, http://dbpedia.org/resource/Rev-ErbA_alpha +
, http://dbpedia.org/resource/THRA +
, http://dbpedia.org/resource/Category:Nuclear_receptors +
, http://dbpedia.org/resource/Transcription_%28biology%29 +
|
| http://dbpedia.org/property/altsymbols
|
ear-1, hRev, Rev-ErbAalpha, THRA1
, BD73, RVR, EAR-1r, HZF2, Hs.37288
|
| http://dbpedia.org/property/arm
|
p
, q
|
| http://dbpedia.org/property/band
|
11.2
, 24.1
|
| http://dbpedia.org/property/chromosome
|
17
, 3
|
| http://dbpedia.org/property/entrezgene
|
9975
, 9572
|
| http://dbpedia.org/property/hgncid
|
7962
, 7963
|
| http://dbpedia.org/property/name
|
http://dbpedia.org/resource/Rev-ErbA_beta +
, http://dbpedia.org/resource/Rev-ErbA_alpha +
|
| http://dbpedia.org/property/omim
|
602408
, 602304
|
| http://dbpedia.org/property/refseq
|
NM_021724
, XM_001130839
|
| http://dbpedia.org/property/symbol
|
http://dbpedia.org/resource/NR1D2 +
, http://dbpedia.org/resource/NR1D1 +
|
| http://dbpedia.org/property/uniprot
|
Q14995
, P20393
|
| http://dbpedia.org/property/wikiPageUsesTemplate
|
http://dbpedia.org/resource/Template:Infobox_protein +
, http://dbpedia.org/resource/Template:Gene-17-stub +
, http://dbpedia.org/resource/Template:Reflist +
, http://dbpedia.org/resource/Template:Transcription_factors +
, http://dbpedia.org/resource/Template:Short_description +
, http://dbpedia.org/resource/Template:MeshName +
, http://dbpedia.org/resource/Template:Receptor/signaling_modulators +
|
| http://purl.org/dc/terms/subject
|
http://dbpedia.org/resource/Category:Nuclear_receptors +
|
| http://www.w3.org/ns/prov#wasDerivedFrom
|
http://en.wikipedia.org/wiki/Rev-Erb?oldid=1103989609&ns=0 +
|
| http://xmlns.com/foaf/0.1/depiction
|
http://commons.wikimedia.org/wiki/Special:FilePath/Model_of_REV-ERB-mediated_Circadian_Gene_Expression.png +
|
| http://xmlns.com/foaf/0.1/isPrimaryTopicOf
|
http://en.wikipedia.org/wiki/Rev-Erb +
|
| http://xmlns.com/foaf/0.1/name
|
nuclear receptor subfamily 1, group D, member 2
, nuclear receptor subfamily 1, group D, member 1
|
| owl:sameAs |
https://global.dbpedia.org/id/39wnc +
, http://fr.dbpedia.org/resource/Rev-erb +
, http://www.wikidata.org/entity/Q3428370 +
, http://dbpedia.org/resource/Rev-Erb +
|
| rdf:type |
http://www.wikidata.org/entity/Q206229 +
, http://dbpedia.org/ontology/Protein +
, http://www.wikidata.org/entity/Q8054 +
, http://dbpedia.org/ontology/Biomolecule +
|
| rdfs:comment |
The Rev-Erb proteins are members of the nu … The Rev-Erb proteins are members of the nuclear receptor (NR) superfamily of intracellular transcription factors and key regulatory components of the circadian clock. There are two forms of the receptor, Rev-Erb alpha and Rev-Erb beta, which are each encoded by a separate gene (NR1D1 and NR1D2, respectively).rate gene (NR1D1 and NR1D2, respectively).
, Les protéines Rev-erb sont des protéines de la superfamille des récepteurs nucléaires. Elles sont notamment impliquées dans la régulation du cycle circadien
|
| rdfs:label |
Rev-Erb
, Rev-erb
|
