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Neopterin ist ein Signal-Botenstoff, der von speziellen körpereigenen Zellen des Immunsystems (Makrophagen) gebildet wird.
, La néoptérine est une ptéridine , intervenant en signalisation cellulaire du système immunitaire de l'organisme en indiquant un état pro-inflammatoire. Elle sert en particulier de marqueur de l'activation de l'immunité cellulaire.
, ネオプテリンはプテリジン骨格を有する化合物で、サイトカインのひとつであるIFN-γ刺激に伴いマクロファージによってグアノシン三リン酸(GTP)から生合成される物質。炎症性免疫の状態(pro-inflammatory immune status)を示し、細胞性免疫の活性指標としてよく使われている。
, Neopterin is a catabolic product of guanos … Neopterin is a catabolic product of guanosine triphosphate (GTP), a purine nucleotide. Neopterin belongs to the chemical group known as pteridines. It is synthesised by human macrophages upon stimulation with the cytokine interferon-gamma and is indicative of a pro-inflammatory immune status. Neopterin serves as a marker of cellular immune system activation. In humans neopterin follows a circadian and circaseptan rhythm.ollows a circadian and circaseptan rhythm.
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| rdfs:comment |
Neopterin ist ein Signal-Botenstoff, der von speziellen körpereigenen Zellen des Immunsystems (Makrophagen) gebildet wird.
, La néoptérine est une ptéridine , intervenant en signalisation cellulaire du système immunitaire de l'organisme en indiquant un état pro-inflammatoire. Elle sert en particulier de marqueur de l'activation de l'immunité cellulaire.
, ネオプテリンはプテリジン骨格を有する化合物で、サイトカインのひとつであるIFN-γ刺激に伴いマクロファージによってグアノシン三リン酸(GTP)から生合成される物質。炎症性免疫の状態(pro-inflammatory immune status)を示し、細胞性免疫の活性指標としてよく使われている。
, Neopterin is a catabolic product of guanos … Neopterin is a catabolic product of guanosine triphosphate (GTP), a purine nucleotide. Neopterin belongs to the chemical group known as pteridines. It is synthesised by human macrophages upon stimulation with the cytokine interferon-gamma and is indicative of a pro-inflammatory immune status. Neopterin serves as a marker of cellular immune system activation. In humans neopterin follows a circadian and circaseptan rhythm.ollows a circadian and circaseptan rhythm.
|
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Neopterin
, ネオプテリン
, Néoptérine
|
