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L'ús de vectors lentivírics en la teràpia … L'ús de vectors lentivírics en la teràpia gènica és un mètode mitjançant el qual poden ser inserits, modificats o eliminats gens de cèl·lules d'organismes que poden ser afectats per lentivirus. Els lentivirus són una família de virus responsables de malalties notables com la sida, que infecten mitjançant la inserció d'ADN al genoma de les cèl·lules hostes. Molts d'aquests virus han estat la base de la investigació que utilitza virus en teràpia gènica, però el lentivirus és únic per la seva capacitat d'infectar cèl·lules que no es divideixen i, per tant, té una gamma més àmplia d'aplicacions potencials. Els lentivirus poden esdevenir (RVE), integrant el seu genoma en el genoma de la línia germinal de l'hoste, de manera que el virus és heretat a partir d'ara pels descendents de l'hoste. Per ser eficaç en la teràpia gènica, hi ha d'haver inserció, alteració i/o eliminació de gens de les cèl·lules hostes. Per fer-ho, els científics utilitzen els mecanismes d'infecció dels lentivirus per aconseguir el resultat desitjat de la teràpia gènica.el resultat desitjat de la teràpia gènica.
, 基因治疗中的慢病毒载体是一种利用慢病毒在生物体內插入、修改或删除基因的方法。有些患者感染艾滋病正是因為慢病毒引起，慢病毒将DNA插入其宿主细胞的基因组後病人便感染艾滋病。在基因治疗中，必须对宿主细胞基因进行插入、改变或去除。为此，科学家们利用慢病毒的感染机制来达到基因治疗的预期效果。
, Lentiviral vectors in gene therapy is a me … Lentiviral vectors in gene therapy is a method by which genes can be inserted, modified, or deleted in organisms using lentivirus. Lentivirus are a family of viruses that are responsible for notable diseases like AIDS, which infect by inserting DNA into their host cells' genome. Many such viruses have been the basis of research using viruses in gene therapy, but the lentivirus is unique in its ability to infect non-dividing cells, and therefore has a wider range of potential applications. Lentiviruses can become endogenous (ERV), integrating their genome into the host germline genome, so that the virus is henceforth inherited by the host's descendants. To be effective in gene therapy, there must be insertion, alteration and/or removal of host cell genes. To do this, scientists use the lentivirus' mechanisms of infection to achieve a desired outcome to gene therapy.achieve a desired outcome to gene therapy.
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L'ús de vectors lentivírics en la teràpia … L'ús de vectors lentivírics en la teràpia gènica és un mètode mitjançant el qual poden ser inserits, modificats o eliminats gens de cèl·lules d'organismes que poden ser afectats per lentivirus. Els lentivirus són una família de virus responsables de malalties notables com la sida, que infecten mitjançant la inserció d'ADN al genoma de les cèl·lules hostes. Molts d'aquests virus han estat la base de la investigació que utilitza virus en teràpia gènica, però el lentivirus és únic per la seva capacitat d'infectar cèl·lules que no es divideixen i, per tant, té una gamma més àmplia d'aplicacions potencials. Els lentivirus poden esdevenir (RVE), integrant el seu genoma en el genoma de la línia germinal de l'hoste, de manera que el virus és heretat a partir d'ara pels descendents de l'hoste. Pertir d'ara pels descendents de l'hoste. Per
, 基因治疗中的慢病毒载体是一种利用慢病毒在生物体內插入、修改或删除基因的方法。有些患者感染艾滋病正是因為慢病毒引起，慢病毒将DNA插入其宿主细胞的基因组後病人便感染艾滋病。在基因治疗中，必须对宿主细胞基因进行插入、改变或去除。为此，科学家们利用慢病毒的感染机制来达到基因治疗的预期效果。
, Lentiviral vectors in gene therapy is a me … Lentiviral vectors in gene therapy is a method by which genes can be inserted, modified, or deleted in organisms using lentivirus. Lentivirus are a family of viruses that are responsible for notable diseases like AIDS, which infect by inserting DNA into their host cells' genome. Many such viruses have been the basis of research using viruses in gene therapy, but the lentivirus is unique in its ability to infect non-dividing cells, and therefore has a wider range of potential applications. Lentiviruses can become endogenous (ERV), integrating their genome into the host germline genome, so that the virus is henceforth inherited by the host's descendants. To be effective in gene therapy, there must be insertion, alteration and/or removal of host cell genes. To do this, scientists use the lentgenes. To do this, scientists use the lent
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Vector lentivíric en teràpia gènica
, 基因治療中的慢病毒載體
, Lentiviral vector in gene therapy
|
