| http://dbpedia.org/ontology/abstract
|
JWH-249 (1-pentyl-3-(2-bromophenylacetyl)i … JWH-249 (1-pentyl-3-(2-bromophenylacetyl)indole) is a synthetic cannabinoid from the phenylacetylindole family, which acts as a cannabinoid agonist with about 2.4 times selectivity for CB1 with a Ki of 8.4 ± 1.8 nM and 20 ± 2 nM at CB2. Similar to the related 2'-methoxy compound JWH-250, the 2'-chloro compound JWH-203, and the 2'-methyl compound JWH-251, JWH-249 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole cannabinoid compounds. In the United States, CB1 receptor agonists of the 3-phenylacetylindole class such as cannabipiperidiethanone are Schedule I Controlled Substances.none are Schedule I Controlled Substances.
|
| http://dbpedia.org/ontology/casNumber
|
864445-60-3
|
| http://dbpedia.org/ontology/chEMBL
|
363471
|
| http://dbpedia.org/ontology/fdaUniiCode
|
H988KQV4U9
|
| http://dbpedia.org/ontology/pubchem
|
44397335
|
| http://dbpedia.org/ontology/thumbnail
|
http://commons.wikimedia.org/wiki/Special:FilePath/JWH-249.svg?width=300 +
|
| http://dbpedia.org/ontology/wikiPageID
|
30163044
|
| http://dbpedia.org/ontology/wikiPageLength
|
3394
|
| http://dbpedia.org/ontology/wikiPageRevisionID
|
947161434
|
| http://dbpedia.org/ontology/wikiPageWikiLink
|
http://dbpedia.org/resource/Category:Bromoarenes +
, http://dbpedia.org/resource/Methyl +
, http://dbpedia.org/resource/Methoxy +
, http://dbpedia.org/resource/JWH-251 +
, http://dbpedia.org/resource/Synthetic_cannabinoid +
, http://dbpedia.org/resource/Schedule_I_Controlled_Substance +
, http://dbpedia.org/resource/Cannabinoid_receptor_2 +
, http://dbpedia.org/resource/AM-679_%28cannabinoid%29 +
, http://dbpedia.org/resource/Aminoalkylindole +
, http://dbpedia.org/resource/Category:Phenylacetylindoles +
, http://dbpedia.org/resource/Phenyl +
, http://dbpedia.org/resource/Category:CB1_receptor_agonists +
, http://dbpedia.org/resource/Category:CB2_receptor_agonists +
, http://dbpedia.org/resource/JWH-250 +
, http://dbpedia.org/resource/Acetyl +
, http://dbpedia.org/resource/Category:JWH_cannabinoids +
, http://dbpedia.org/resource/Chloro +
, http://dbpedia.org/resource/Cannabinoid +
, http://dbpedia.org/resource/Dissociation_constant +
, http://dbpedia.org/resource/JWH-203 +
, http://dbpedia.org/resource/Cannabinoid_receptor_1 +
, http://dbpedia.org/resource/Naphthoyl +
, http://dbpedia.org/resource/Cannabinoid_agonist +
, http://dbpedia.org/resource/Phenylacetylindole +
|
| http://dbpedia.org/property/br
|
1
|
| http://dbpedia.org/property/c
|
21
|
| http://dbpedia.org/property/casNumber
|
864445
|
| http://dbpedia.org/property/chembl
|
363471
|
| http://dbpedia.org/property/chemspiderid
|
23253217
|
| http://dbpedia.org/property/h
|
22
|
| http://dbpedia.org/property/iupacName
|
2
|
| http://dbpedia.org/property/legalCa
|
Schedule II
|
| http://dbpedia.org/property/legalDe
|
NpSG
|
| http://dbpedia.org/property/legalUk
|
PSA
|
| http://dbpedia.org/property/legalUs
|
Schedule I
|
| http://dbpedia.org/property/n
|
1
|
| http://dbpedia.org/property/o
|
1
|
| http://dbpedia.org/property/pubchem
|
44397335
|
| http://dbpedia.org/property/smiles
|
CCCCCn1ccCCc3ccccc3Br
|
| http://dbpedia.org/property/stdinchi
|
1
|
| http://dbpedia.org/property/stdinchikey
|
CGQRVOHECAULLB-UHFFFAOYSA-N
|
| http://dbpedia.org/property/unii
|
H988KQV4U9
|
| http://dbpedia.org/property/verifiedfields
|
changed
|
| http://dbpedia.org/property/verifiedrevid
|
477496189
|
| http://dbpedia.org/property/width
|
150
|
| http://dbpedia.org/property/wikiPageUsesTemplate
|
http://dbpedia.org/resource/Template:Stdinchicite +
, http://dbpedia.org/resource/Template:Cascite +
, http://dbpedia.org/resource/Template:Chemspidercite +
, http://dbpedia.org/resource/Template:Cannabinoid-stub +
, http://dbpedia.org/resource/Template:Cannabinoids +
, http://dbpedia.org/resource/Template:Reflist +
, http://dbpedia.org/resource/Template:Ebicite +
, http://dbpedia.org/resource/Template:Drugbox +
, http://dbpedia.org/resource/Template:Fdacite +
, http://dbpedia.org/resource/Template:Drugbankcite +
|
| http://purl.org/dc/terms/subject
|
http://dbpedia.org/resource/Category:CB1_receptor_agonists +
, http://dbpedia.org/resource/Category:CB2_receptor_agonists +
, http://dbpedia.org/resource/Category:JWH_cannabinoids +
, http://dbpedia.org/resource/Category:Bromoarenes +
, http://dbpedia.org/resource/Category:Phenylacetylindoles +
|
| http://purl.org/linguistics/gold/hypernym
|
http://dbpedia.org/resource/Cannabinoid +
|
| http://www.w3.org/ns/prov#wasDerivedFrom
|
http://en.wikipedia.org/wiki/JWH-249?oldid=947161434&ns=0 +
|
| http://xmlns.com/foaf/0.1/depiction
|
http://commons.wikimedia.org/wiki/Special:FilePath/JWH-249.svg +
|
| http://xmlns.com/foaf/0.1/isPrimaryTopicOf
|
http://en.wikipedia.org/wiki/JWH-249 +
|
| owl:sameAs |
http://sh.dbpedia.org/resource/JWH-249 +
, http://sr.dbpedia.org/resource/JWH-249 +
, http://www.wikidata.org/entity/Q6109216 +
, http://rdf.freebase.com/ns/m.0g54n4p +
, http://dbpedia.org/resource/JWH-249 +
, https://global.dbpedia.org/id/4oCpZ +
|
| rdf:type |
http://www.wikidata.org/entity/Q8386 +
, http://dbpedia.org/ontology/ChemicalSubstance +
, http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#ChemicalObject +
, http://dbpedia.org/ontology/Drug +
|
| rdfs:comment |
JWH-249 (1-pentyl-3-(2-bromophenylacetyl)i … JWH-249 (1-pentyl-3-(2-bromophenylacetyl)indole) is a synthetic cannabinoid from the phenylacetylindole family, which acts as a cannabinoid agonist with about 2.4 times selectivity for CB1 with a Ki of 8.4 ± 1.8 nM and 20 ± 2 nM at CB2. Similar to the related 2'-methoxy compound JWH-250, the 2'-chloro compound JWH-203, and the 2'-methyl compound JWH-251, JWH-249 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole cannabinoid compounds.st aminoalkylindole cannabinoid compounds.
|
| rdfs:label |
JWH-249
|
