| http://dbpedia.org/ontology/abstract
|
Hemorphin-4 is an endogenous opioid peptid … Hemorphin-4 is an endogenous opioid peptide of the hemorphin family which possesses antinociceptive properties and is derived from the β-chain of hemoglobin in the bloodstream. It is a tetrapeptide with the amino acid sequence Tyr-Pro-Trp-Thr. Hemorphin-4 has affinities for the μ-, δ-, and κ-opioid receptors that are in the same range as the structurally related β-casomorphins, although affinity to the κ-opioid receptor is markedly higher in comparison. It acts as an agonist at these sites. Hemorphin-4 also has inhibitory effects on angiotensin-converting enzyme (ACE), and as a result, may play a role in the regulation of blood pressure. Notably, inhibition of ACE also reduces enkephalin catabolism.of ACE also reduces enkephalin catabolism.
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| http://dbpedia.org/ontology/alternativeName
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L-tyrosyl-L-prolyl-L-tryptophyl-L-threonine
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| http://dbpedia.org/ontology/iupacName
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(2S,3R)-2-(2S)-2-[[(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-hydroxybutanoic acid
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http://commons.wikimedia.org/wiki/Special:FilePath/Hemorphin_4.svg?width=300 +
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33863877
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4610
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1096103309
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Hemorphin 4.svg
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300
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| http://dbpedia.org/property/iupacname
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-2
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| http://dbpedia.org/property/othernames
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L-tyrosyl-L-prolyl-L-tryptophyl-L-threonine
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|
| rdfs:comment |
Hemorphin-4 is an endogenous opioid peptid … Hemorphin-4 is an endogenous opioid peptide of the hemorphin family which possesses antinociceptive properties and is derived from the β-chain of hemoglobin in the bloodstream. It is a tetrapeptide with the amino acid sequence Tyr-Pro-Trp-Thr. Hemorphin-4 has affinities for the μ-, δ-, and κ-opioid receptors that are in the same range as the structurally related β-casomorphins, although affinity to the κ-opioid receptor is markedly higher in comparison. It acts as an agonist at these sites. Hemorphin-4 also has inhibitory effects on angiotensin-converting enzyme (ACE), and as a result, may play a role in the regulation of blood pressure. Notably, inhibition of ACE also reduces enkephalin catabolism.of ACE also reduces enkephalin catabolism.
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| rdfs:label |
Hemorphin-4
|
