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The gntR-DTE RNA motif is a conserved RNA … The gntR-DTE RNA motif is a conserved RNA structure that was discovered by bioinformatics.gntR-DTE motifs are found in some, but not all species within the genus Streptomyces. It is ambiguous whether gntR-DTE RNAs function as cis-regulatory elements or whether they operate in trans as small RNAs. Of the 7 known examples of gntR RNAs, 6 are upstream of protein-coding genes, suggesting a cis-regulatory function. However, having more than 10% of the RNAs no upstream of a protein-coding gene would be unusually high for a cis-regulatory RNA. Additionally, the reverse-complement of the RNA would be consistently upstream of protein-coding genes, of which most encode helix-turn-helix proteins of the XRE-like family. However, there is no other evidence to suggest that the RNA is transcribed from the opposite strand.A is transcribed from the opposite strand.
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1994
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Consensus secondary structure and sequence conservation of gntR-DTE RNA
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gntR-DTE
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rdfs:comment |
The gntR-DTE RNA motif is a conserved RNA … The gntR-DTE RNA motif is a conserved RNA structure that was discovered by bioinformatics.gntR-DTE motifs are found in some, but not all species within the genus Streptomyces. It is ambiguous whether gntR-DTE RNAs function as cis-regulatory elements or whether they operate in trans as small RNAs. Of the 7 known examples of gntR RNAs, 6 are upstream of protein-coding genes, suggesting a cis-regulatory function. However, having more than 10% of the RNAs no upstream of a protein-coding gene would be unusually high for a cis-regulatory RNA. Additionally, the reverse-complement of the RNA would be consistently upstream of protein-coding genes, of which most encode helix-turn-helix proteins of the XRE-like family. However, there is no other evidence to suggest that the RNA is transcribed from thuggest that the RNA is transcribed from th
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rdfs:label |
GntR-DTE RNA motif
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