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La glycocyamine, ou acide guanidinoacétiqu … La glycocyamine, ou acide guanidinoacétique, est un composé chimique de formule HOOC–CH2–N=C(NH2)2. C'est un métabolite du cycle de l'urée et du métabolisme de nombreux acides aminés, notamment de l'arginine, de la glycine, de la proline, de la sérine et de la thréonine. La glycocyamine est également un précurseur direct de la créatine, d'où son utilisation comme complément alimentaire (culturisme). La métabolisation de la glycocyamine en créatine dans le foie conduit cependant à réduire le taux de groupes méthyle disponibles pour le métabolisme général, d'où augmentation du taux d'homocystéine responsable de troubles squelettiques et cardiovasculaires.oubles squelettiques et cardiovasculaires.
, Guanidinoessigsäure (Guanidinoacetat, oder … Guanidinoessigsäure (Guanidinoacetat, oder englisch guanidinoacetic acid, GAA) wird im Organismus von Wirbeltieren aus Glycin durch Guanylierung (Übertragung einer Guanidin-Gruppe aus Arginin) gebildet und durch anschließende Methylierung in Kreatin umgewandelt. Sie ist selbst keine Aminosäure, spielt aber ebenfalls eine Rolle im Metabolismus der kanonischen Aminosäuren Serin, Threonin und Prolin. GAA wird als Futtermittelzusatzstoff bei der Geflügel- und Schweinemast eingesetzt.der Geflügel- und Schweinemast eingesetzt.
, La glicociamina (o guanidinoacetato) es un … La glicociamina (o guanidinoacetato) es un metabolito de la glicina en el cual el grupo amino ha sido convertido en un grupo guanidino. La glicociamina es un precursor directo de la creatina y suele utilizarse como suplemento dietario. Sin embargo el metabolismo de la creatina a partir de la glicociamina provoca el agotamiento de las reservas hepáticas de grupos metilo; esto a su vez causa que los niveles de homocisteína se eleven, lo que se ha demostrado que provoca problemas cardiovasculares y esqueléticos.problemas cardiovasculares y esqueléticos.
, Glycocyamine (or guanidinoacetate) is a me … Glycocyamine (or guanidinoacetate) is a metabolite of glycine in which the amino group has been converted into a guanidine by guanylation (transfer of a guanidine group from arginine). In vertebrate organism it is then transformed into creatine by methylation. Glycocyamine is used as a supplement and as a feed additive in poultry farming. However, the metabolism of creatine from glycocyamine in the liver causes a depletion of methyl groups. This causes homocysteine levels to rise, which has been shown to produce cardiovascular and skeletal problems. Glycocyamine plays a role in the metabolism of the amino acids serine, threonine and proline.amino acids serine, threonine and proline.
, Guanidinoazijnzuur (ook guanidinoacetaat o … Guanidinoazijnzuur (ook guanidinoacetaat of glycocyamine genoemd) is een organische verbinding die van nature voorkomt in gewervelden, ook in de mens. Het is een metaboliet van glycine, waarin de aminogroep is omgezet in een guanidine. Guanidinoazijnzuur is de rechtstreekse metabolische voorloper van creatine. Net zoals creatine wordt het in het lichaam gevormd maar het kan ook ingenomen worden via de voeding en meer bepaald via voedingssupplementen. Synthetisch guanidinoazijnzuur wordt ook toegevoegd aan diervoeder; in de Europese Unie is het toegelaten in voeder voor mestkippen, gespeende biggen en mestvarkens.stkippen, gespeende biggen en mestvarkens.
, 胍基乙酸 (英語：Glycocyamine)是一种甘氨酸的代谢中间产物，其氨基被胍基取代。 胍基乙酸是肌酸生物合成的直接前体（如下图）。 但这一反应会造成高半胱氨酸水平的升高，导致一些心血管问题。
, 글리코사이아민(영어: glycocyamine) 또는 2-구아니디노아세트산(영 … 글리코사이아민(영어: glycocyamine) 또는 2-구아니디노아세트산(영어: 2-guanidinoacetic acid)은 아미노기가 구아닐화(아르지닌으로부터 구아니디노기의 전이)에 의해 구아니딘으로 전환된 글리신의 대사산물이다. 척추동물에서 글리코사이아민은 메틸화에 의해 크레아틴으로 전환된다. 글리코사이아민은 에서 보충제 및 로 사용된다. 그러나 간에서 글리코사이아민으로부터 크레아틴으로의 대사는 메틸기의 고갈을 야기한다. 이것은 호모시스테인의 수준을 상승시켜 심혈관계 및 골격근에 문제를 일으키는 것으로 나타났다. 글리코사이아민 자체는 아미노산이 아니지만, 아미노산인 세린, 트레오닌 및 프롤린의 대사에서 중요한 역할을 한다.지만, 아미노산인 세린, 트레오닌 및 프롤린의 대사에서 중요한 역할을 한다.
, グアニジノ酢酸（guanidinoacetate）またはグリコシアミン（Glycocyamine）は、グリシンのアミノ基がグアニジンに変換された代謝産物である。（EC 2.1.4.1）によってグリシンとアルギニンから合成され、グアニジノ酢酸-N-メチルトランスフェラーゼ（EC 2.1.1.2）によってメチル化されてクレアチンとなる。
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Guanidinoessigsäure (Guanidinoacetat, oder … Guanidinoessigsäure (Guanidinoacetat, oder englisch guanidinoacetic acid, GAA) wird im Organismus von Wirbeltieren aus Glycin durch Guanylierung (Übertragung einer Guanidin-Gruppe aus Arginin) gebildet und durch anschließende Methylierung in Kreatin umgewandelt. Sie ist selbst keine Aminosäure, spielt aber ebenfalls eine Rolle im Metabolismus der kanonischen Aminosäuren Serin, Threonin und Prolin. GAA wird als Futtermittelzusatzstoff bei der Geflügel- und Schweinemast eingesetzt.der Geflügel- und Schweinemast eingesetzt.
, Glycocyamine (or guanidinoacetate) is a me … Glycocyamine (or guanidinoacetate) is a metabolite of glycine in which the amino group has been converted into a guanidine by guanylation (transfer of a guanidine group from arginine). In vertebrate organism it is then transformed into creatine by methylation. transformed into creatine by methylation.
, 胍基乙酸 (英語：Glycocyamine)是一种甘氨酸的代谢中间产物，其氨基被胍基取代。 胍基乙酸是肌酸生物合成的直接前体（如下图）。 但这一反应会造成高半胱氨酸水平的升高，导致一些心血管问题。
, グアニジノ酢酸（guanidinoacetate）またはグリコシアミン（Glycocyamine）は、グリシンのアミノ基がグアニジンに変換された代謝産物である。（EC 2.1.4.1）によってグリシンとアルギニンから合成され、グアニジノ酢酸-N-メチルトランスフェラーゼ（EC 2.1.1.2）によってメチル化されてクレアチンとなる。
, La glicociamina (o guanidinoacetato) es un … La glicociamina (o guanidinoacetato) es un metabolito de la glicina en el cual el grupo amino ha sido convertido en un grupo guanidino. La glicociamina es un precursor directo de la creatina y suele utilizarse como suplemento dietario. Sin embargo el metabolismo de la creatina a partir de la glicociamina provoca el agotamiento de las reservas hepáticas de grupos metilo; esto a su vez causa que los niveles de homocisteína se eleven, lo que se ha demostrado que provoca problemas cardiovasculares y esqueléticos.problemas cardiovasculares y esqueléticos.
, 글리코사이아민(영어: glycocyamine) 또는 2-구아니디노아세트산(영 … 글리코사이아민(영어: glycocyamine) 또는 2-구아니디노아세트산(영어: 2-guanidinoacetic acid)은 아미노기가 구아닐화(아르지닌으로부터 구아니디노기의 전이)에 의해 구아니딘으로 전환된 글리신의 대사산물이다. 척추동물에서 글리코사이아민은 메틸화에 의해 크레아틴으로 전환된다. 글리코사이아민은 에서 보충제 및 로 사용된다. 그러나 간에서 글리코사이아민으로부터 크레아틴으로의 대사는 메틸기의 고갈을 야기한다. 이것은 호모시스테인의 수준을 상승시켜 심혈관계 및 골격근에 문제를 일으키는 것으로 나타났다. 글리코사이아민 자체는 아미노산이 아니지만, 아미노산인 세린, 트레오닌 및 프롤린의 대사에서 중요한 역할을 한다.지만, 아미노산인 세린, 트레오닌 및 프롤린의 대사에서 중요한 역할을 한다.
, Guanidinoazijnzuur (ook guanidinoacetaat of glycocyamine genoemd) is een organische verbinding die van nature voorkomt in gewervelden, ook in de mens. Het is een metaboliet van glycine, waarin de aminogroep is omgezet in een guanidine.
, La glycocyamine, ou acide guanidinoacétiqu … La glycocyamine, ou acide guanidinoacétique, est un composé chimique de formule HOOC–CH2–N=C(NH2)2. C'est un métabolite du cycle de l'urée et du métabolisme de nombreux acides aminés, notamment de l'arginine, de la glycine, de la proline, de la sérine et de la thréonine. proline, de la sérine et de la thréonine.
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Guanidinoazijnzuur
, 글리코사이아민
, Glicociamina
, 胍基乙酸
, Glycocyamine
, Guanidinoessigsäure
, グアニジノ酢酸
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