| http://dbpedia.org/ontology/abstract
|
The GAF domain is a type of protein domain … The GAF domain is a type of protein domain that is found in a wide range of proteins from all species. The GAF domain is named after some of the proteins it is found in: cGMP-specific phosphodiesterases, adenylyl cyclases and FhlA. The first structure of a GAF domain solved by Ho and colleagues showed that this domain shared a similar fold with the PAS domain. In mammals, GAF domains are found in five members of the cyclic nucleotide phosphodiesterase superfamily: PDE2, PDE5, and PDE6 which bind cGMP to the GAF domain, PDE10 which binds cAMP, and PDE11 which binds both cGMP and cAMP. and PDE11 which binds both cGMP and cAMP.
|
| http://dbpedia.org/ontology/symbol
|
GAF
|
| http://dbpedia.org/ontology/thumbnail
|
http://commons.wikimedia.org/wiki/Special:FilePath/PDB_1mc0_EBI.jpg?width=300 +
|
| http://dbpedia.org/ontology/wikiPageID
|
28277542
|
| http://dbpedia.org/ontology/wikiPageLength
|
3385
|
| http://dbpedia.org/ontology/wikiPageRevisionID
|
1041370238
|
| http://dbpedia.org/ontology/wikiPageWikiLink
|
http://dbpedia.org/resource/Protein_domain +
, http://dbpedia.org/resource/Category:Protein_domains +
, http://dbpedia.org/resource/PDE10A +
, http://dbpedia.org/resource/PDE11A +
, http://dbpedia.org/resource/PDE2A +
, http://dbpedia.org/resource/CGMP-specific_phosphodiesterase_type_5 +
, http://dbpedia.org/resource/PAS_domain +
, http://dbpedia.org/resource/PDE6B +
, http://dbpedia.org/resource/PDE6A +
, http://dbpedia.org/resource/PDE6C +
|
| http://dbpedia.org/property/caption
|
180.0
|
| http://dbpedia.org/property/interpro
|
IPR003018
|
| http://dbpedia.org/property/name
|
GAF domain
|
| http://dbpedia.org/property/pfam
|
PF01590
|
| http://dbpedia.org/property/pfamClan
|
CL0161
|
| http://dbpedia.org/property/scop
|
1
|
| http://dbpedia.org/property/smart
|
GAF
|
| http://dbpedia.org/property/symbol
|
GAF
|
| http://dbpedia.org/property/wikiPageUsesTemplate
|
http://dbpedia.org/resource/Template:Reflist +
, http://dbpedia.org/resource/Template:Infobox_protein_family +
|
| http://purl.org/dc/terms/subject
|
http://dbpedia.org/resource/Category:Protein_domains +
|
| http://purl.org/linguistics/gold/hypernym
|
http://dbpedia.org/resource/Domain +
|
| http://www.w3.org/ns/prov#wasDerivedFrom
|
http://en.wikipedia.org/wiki/GAF_domain?oldid=1041370238&ns=0 +
|
| http://xmlns.com/foaf/0.1/depiction
|
http://commons.wikimedia.org/wiki/Special:FilePath/PDB_1mc0_EBI.jpg +
|
| http://xmlns.com/foaf/0.1/isPrimaryTopicOf
|
http://en.wikipedia.org/wiki/GAF_domain +
|
| owl:sameAs |
http://dbpedia.org/resource/GAF_domain +
, http://www.wikidata.org/entity/Q24723594 +
, http://rdf.freebase.com/ns/m.0cp0ln2 +
, https://global.dbpedia.org/id/2Ksnw +
|
| rdf:type |
http://dbpedia.org/class/yago/Organization108008335 +
, http://dbpedia.org/class/yago/YagoPermanentlyLocatedEntity +
, http://dbpedia.org/class/yago/YagoLegalActorGeo +
, http://dbpedia.org/class/yago/YagoLegalActor +
, http://dbpedia.org/class/yago/Family108078020 +
, http://dbpedia.org/class/yago/Abstraction100002137 +
, http://dbpedia.org/ontology/Protein +
, http://www.wikidata.org/entity/Q206229 +
, http://dbpedia.org/ontology/Biomolecule +
, http://dbpedia.org/class/yago/SocialGroup107950920 +
, http://dbpedia.org/class/yago/Unit108189659 +
, http://www.wikidata.org/entity/Q8054 +
, http://dbpedia.org/class/yago/Group100031264 +
|
| rdfs:comment |
The GAF domain is a type of protein domain … The GAF domain is a type of protein domain that is found in a wide range of proteins from all species. The GAF domain is named after some of the proteins it is found in: cGMP-specific phosphodiesterases, adenylyl cyclases and FhlA. The first structure of a GAF domain solved by Ho and colleagues showed that this domain shared a similar fold with the PAS domain. In mammals, GAF domains are found in five members of the cyclic nucleotide phosphodiesterase superfamily: PDE2, PDE5, and PDE6 which bind cGMP to the GAF domain, PDE10 which binds cAMP, and PDE11 which binds both cGMP and cAMP. and PDE11 which binds both cGMP and cAMP.
|
| rdfs:label |
GAF domain
|
