| http://dbpedia.org/ontology/abstract
|
Il fluocinolone acetonide è un corticosteroide, derivato sintetico dell'idrocortisone, utilizzato in particolare in dermatologia per ridurre un processo infiammatorio a livello della pelle.
, Флуоцинолона ацетонид (Fluocinolone aceton … Флуоцинолона ацетонид (Fluocinolone acetonide) — противовоспалительное лекарственное средство, глюкокортикостероид, применяется в виде мази для наружного применения. Выпускается под наименованиями«Синафлан», «Флуцинар», «Синалар», «Синодерм», «Флукорт», «Эзацинон».налар», «Синодерм», «Флукорт», «Эзацинон».
, Fluocinolone acetonide is a corticosteroid … Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocortisone derivative. The fluorine substitution at position 9 in the steroid nucleus greatly enhances its activity. It was first synthesized in 1959 in the Research Department of Syntex Laboratories S.A. Mexico City. Preparations containing it were first marketed under the name Synalar. A typical dosage strength used in dermatology is 0.01–0.025%. One such cream is sold under the brand name Flucort-N and includes the antibiotic neomycin. Fluocinolone acetonide was also found to strongly potentiate TGF-β-associated chondrogenesis of bone marrow mesenchymal stem/progenitor cells, by increasing the levels of collagen type II by more than 100 fold compared to the widely used dexamethasone. Fluocinolone acetonide intravitreal implants have been used to treat non-infectious uveitis. A systematic review could not determine whether fluocinolone acetonide implants are superior to standard of care treatment for uveitis. A fluocinolone acetonide intravitreal implant with the brand name Iluvien is sold by biopharmaceutical company Alimera Sciences to treat diabetic macular edema (DME). It was approved for medical use in 1961.. It was approved for medical use in 1961.
, Fluocynolon – organiczny związek chemiczny … Fluocynolon – organiczny związek chemiczny, syntetyczny, fluorowany steroidowy lek przeciwzapalny i przeciwuczuleniowy. Zmniejsza obrzęk oraz przepuszczalność naczyń włosowatych. Siła działania przeciwzapalnego, przeciwuczuleniowego i kurczącego naczynia krwionośne jest porównywalna z triamcynolonem.onośne jest porównywalna z triamcynolonem.
, Acetónido de fluocinolona es un corticoste … Acetónido de fluocinolona es un corticosteroide potente de grado III, empleado fundamentalmente en dermatología para reducir la inflamación de la piel y reducir el prurito o picor. Es un derivado sintético de hidrocortisona y fue sintetizado por primera vez en 1959 en el departamento de investigación de Syntex Laboratories S.A. de Ciudad de México. El átomo de flúor sustituido en la posición 9 del núcleo esteroide aumenta su actividad. La dosis típica usada en dermatología es 0.01–0.025%.[cita requerida]rmatología es 0.01–0.025%.[cita requerida]
, Fluocinolona acetonida é um corticosteroid … Fluocinolona acetonida é um corticosteroide primariamente usado em dermatologia para reduzir inflamação da pele e aliviar coceiras. É uma derivado sintético da hidrocortisona. A substituição de flúor na posição 9 no núcleo de esteróides aumenta grandemente a sua atividade. Foi sintetizado pela primeira vez em 1959 no Departamento de Pesquisa da Syntex Laboratories S.A, Cidade do México City. Preparações que o continham foram comercializados pela primeira vez sob o nome Synalar. Uma dosagem típica utilizada em dermatologia é 0,01–0,025%. Um desses cremes é vendido sob a marca Flucort-N e inclui o antibiótico neomicina. Fluocinolona acetonida tem também sido encontrada em associada a TGF-β fortemente potencializada de células mesenimáticas/progenitoras da medula óssea, aumentando os níveis de colágeno tipo II por mais de 100 vezes comparado a amplamente usada dexametasona. Implantes intravíricos de fluocinolona acetonida tem sido utilizados para tratar uveítes não infecciosas. Uma revisão sistemática não pode determinar se implantes de fluocinolona acetonida são superiores ao tratamento padrão de cuidados para uveítes.ratamento padrão de cuidados para uveítes.
, 醋酸氟轻松（英文：Fluocinolone acetonide）是一种皮质类固醇，主要用于治疗皮肤病，减少皮肤炎症和缓解瘙痒。 它是合成的氢化可的松衍生物。类固醇核中第9位的氟取代大大增强了它的活性。它于1959年在墨西哥城Syntex实验室研究部门首次合成。含有醋酸氟轻松的药膏最初以仙乃乐（Synalar）的注册商标进行销售。治疗皮肤病的药膏中使用的氟轻松的典型剂量为0.01-0.025％。但氟轻松作为一种外用類固醇藥物不能殺菌，反而會助長細菌滋生，所以不能用於感染性皮膚病，例如癬和疥瘡。
|
| http://dbpedia.org/ontology/alternativeName
|
Synalar, Iluvien, others
|
| http://dbpedia.org/ontology/casNumber
|
67-73-2
|
| http://dbpedia.org/ontology/chEBI
|
31623
|
| http://dbpedia.org/ontology/chEMBL
|
989
|
| http://dbpedia.org/ontology/drugbank
|
DB00591
|
| http://dbpedia.org/ontology/fdaUniiCode
|
0CD5FD6S2M
|
| http://dbpedia.org/ontology/kegg
|
D01825
|
| http://dbpedia.org/ontology/pubchem
|
6215
|
| http://dbpedia.org/ontology/thumbnail
|
http://commons.wikimedia.org/wiki/Special:FilePath/Fluocinolone_acetonide.svg?width=300 +
|
| http://dbpedia.org/ontology/wikiPageExternalLink
|
https://druginfo.nlm.nih.gov/drugportal/name/fluocinolone%20acetonide +
|
| http://dbpedia.org/ontology/wikiPageID
|
6717296
|
| http://dbpedia.org/ontology/wikiPageLength
|
6369
|
| http://dbpedia.org/ontology/wikiPageRevisionID
|
1095445163
|
| http://dbpedia.org/ontology/wikiPageWikiLink
|
http://dbpedia.org/resource/Uveitis +
, http://dbpedia.org/resource/Diabetic_macular_edema +
, http://dbpedia.org/resource/Category:Substances_discovered_in_the_1950s +
, http://dbpedia.org/resource/Category:Diketones +
, http://dbpedia.org/resource/Category:Corticosteroid_cyclic_ketals +
, http://dbpedia.org/resource/Ciprocinonide +
, http://dbpedia.org/resource/Category:Acetonides +
, http://dbpedia.org/resource/Dermatology +
, http://dbpedia.org/resource/Topical_steroid +
, http://dbpedia.org/resource/Chondrogenesis +
, http://dbpedia.org/resource/Category:Glucocorticoids +
, http://dbpedia.org/resource/Corticosteroid +
, http://dbpedia.org/resource/Category:Otologicals +
, http://dbpedia.org/resource/Liver +
, http://dbpedia.org/resource/Fluocinonide +
, http://dbpedia.org/resource/Category:Corticosteroids +
, http://dbpedia.org/resource/CYP3A4 +
, http://dbpedia.org/resource/Alimera_Sciences +
, http://dbpedia.org/resource/Glucocorticoid +
, http://dbpedia.org/resource/Neomycin +
, http://dbpedia.org/resource/Category:Fluoroarenes +
, http://dbpedia.org/resource/Hydrocortisone +
, http://dbpedia.org/resource/Category:Diols +
|
| http://dbpedia.org/property/atcPrefix
|
5.0
|
| http://dbpedia.org/property/atcSuffix
|
AA10
|
| http://dbpedia.org/property/c
|
24
|
| http://dbpedia.org/property/casNumber
|
67
|
| http://dbpedia.org/property/chebi
|
31623
|
| http://dbpedia.org/property/chembl
|
989
|
| http://dbpedia.org/property/chemspiderid
|
5980
|
| http://dbpedia.org/property/drugbank
|
DB00591
|
| http://dbpedia.org/property/eliminationHalfLife
|
6120.0
|
| http://dbpedia.org/property/f
|
2
|
| http://dbpedia.org/property/h
|
30
|
| http://dbpedia.org/property/image
|
Fluocinolone acetonide .png
|
| http://dbpedia.org/property/iupacName
|
-1219
|
| http://dbpedia.org/property/iupharLigand
|
7077
|
| http://dbpedia.org/property/kegg
|
D01825
|
| http://dbpedia.org/property/legalAu
|
S4
|
| http://dbpedia.org/property/legalCa
|
Rx-only
|
| http://dbpedia.org/property/legalStatus
|
Rx-only
|
| http://dbpedia.org/property/legalUk
|
POM
|
| http://dbpedia.org/property/legalUs
|
Rx-only
|
| http://dbpedia.org/property/metabolism
|
Liver, CYP3A4-mediated
|
| http://dbpedia.org/property/o
|
6
|
| http://dbpedia.org/property/pregnancyAu
|
A
|
| http://dbpedia.org/property/pubchem
|
6215
|
| http://dbpedia.org/property/routesOfAdministration
|
Topical, ophthalmic intravitreal injection
|
| http://dbpedia.org/property/smiles
|
O=C\1\C=C5/[C@@][C@]2[C@H]C[C@@H]5F
|
| http://dbpedia.org/property/stdinchi
|
1
|
| http://dbpedia.org/property/stdinchikey
|
FEBLZLNTKCEFIT-VSXGLTOVSA-N
|
| http://dbpedia.org/property/tradename
|
Synalar, Iluvien, others
|
| http://dbpedia.org/property/unii
|
0
|
| http://dbpedia.org/property/verifiedfields
|
changed
|
| http://dbpedia.org/property/verifiedrevid
|
461101531
|
| http://dbpedia.org/property/wikiPageUsesTemplate
|
http://dbpedia.org/resource/Template:Drugbankcite +
, http://dbpedia.org/resource/Template:ATC +
, http://dbpedia.org/resource/Template:Glucocorticoidics +
, http://dbpedia.org/resource/Template:Keggcite +
, http://dbpedia.org/resource/Template:Citation_needed +
, http://dbpedia.org/resource/Template:Drugbox +
, http://dbpedia.org/resource/Template:Short_description +
, http://dbpedia.org/resource/Template:Drugs.com +
, http://dbpedia.org/resource/Template:Fdacite +
, http://dbpedia.org/resource/Template:Cardiovascular-drug-stub +
, http://dbpedia.org/resource/Template:Portal_bar +
, http://dbpedia.org/resource/Template:Ophthalmology-stub +
, http://dbpedia.org/resource/Template:Cascite +
, http://dbpedia.org/resource/Template:Chemspidercite +
, http://dbpedia.org/resource/Template:Otologicals +
, http://dbpedia.org/resource/Template:Vasoprotectives +
, http://dbpedia.org/resource/Template:Glucocorticoids +
, http://dbpedia.org/resource/Template:Dermatologic-drug-stub +
, http://dbpedia.org/resource/Template:Cite_web +
, http://dbpedia.org/resource/Template:Ebicite +
, http://dbpedia.org/resource/Template:Reflist +
, http://dbpedia.org/resource/Template:Stdinchicite +
|
| http://purl.org/dc/terms/subject
|
http://dbpedia.org/resource/Category:Diols +
, http://dbpedia.org/resource/Category:Fluoroarenes +
, http://dbpedia.org/resource/Category:Otologicals +
, http://dbpedia.org/resource/Category:Diketones +
, http://dbpedia.org/resource/Category:Glucocorticoids +
, http://dbpedia.org/resource/Category:Acetonides +
, http://dbpedia.org/resource/Category:Corticosteroid_cyclic_ketals +
, http://dbpedia.org/resource/Category:Corticosteroids +
, http://dbpedia.org/resource/Category:Substances_discovered_in_the_1950s +
|
| http://purl.org/linguistics/gold/hypernym
|
http://dbpedia.org/resource/Corticosteroid +
|
| http://www.w3.org/ns/prov#wasDerivedFrom
|
http://en.wikipedia.org/wiki/Fluocinolone_acetonide?oldid=1095445163&ns=0 +
|
| http://xmlns.com/foaf/0.1/depiction
|
http://commons.wikimedia.org/wiki/Special:FilePath/Fluocinolone_acetonide_%28Ball-n-Stick%29.png +
, http://commons.wikimedia.org/wiki/Special:FilePath/Fluocinolone_acetonide.svg +
|
| http://xmlns.com/foaf/0.1/isPrimaryTopicOf
|
http://en.wikipedia.org/wiki/Fluocinolone_acetonide +
|
| owl:sameAs |
http://es.dbpedia.org/resource/Acet%C3%B3nido_de_fluocinolona +
, http://hu.dbpedia.org/resource/Fluocinolon-acetonid +
, http://vi.dbpedia.org/resource/Fluocinolone_acetonide +
, http://pt.dbpedia.org/resource/Fluocinolona_acetonida +
, http://yago-knowledge.org/resource/Fluocinolone_acetonide +
, https://global.dbpedia.org/id/54ozq +
, http://rdf.freebase.com/ns/m.0gk4vx +
, http://ru.dbpedia.org/resource/%D0%A4%D0%BB%D1%83%D0%BE%D1%86%D0%B8%D0%BD%D0%BE%D0%BB%D0%BE%D0%BD%D0%B0_%D0%B0%D1%86%D0%B5%D1%82%D0%BE%D0%BD%D0%B8%D0%B4 +
, http://zh.dbpedia.org/resource/%E9%86%8B%E9%85%B8%E6%B0%9F%E8%BD%BB%E6%9D%BE +
, http://it.dbpedia.org/resource/Fluocinolone_acetonide +
, http://sr.dbpedia.org/resource/Fluocinolon_acetonid +
, http://azb.dbpedia.org/resource/%D9%81%D9%84%D9%88%D8%A6%D9%88%D8%B3%DB%8C%D9%86%D9%88%D9%84%D9%88%D9%86 +
, http://ca.dbpedia.org/resource/Acet%C3%B2nid_de_fluocinolona +
, http://pl.dbpedia.org/resource/Fluocynolon +
, http://fa.dbpedia.org/resource/%D9%81%D9%84%D9%88%D8%A6%D9%88%D8%B3%DB%8C%D9%86%D9%88%D9%84%D9%88%D9%86 +
, http://www4.wiwiss.fu-berlin.de/sider/resource/drugs/3381 +
, http://www.wikidata.org/entity/Q924467 +
, http://dbpedia.org/resource/Fluocinolone_acetonide +
, http://sh.dbpedia.org/resource/Fluocinolon_acetonid +
, http://www4.wiwiss.fu-berlin.de/drugbank/resource/drugs/DB00591 +
|
| rdf:type |
http://dbpedia.org/class/yago/Communication100033020 +
, http://dbpedia.org/class/yago/Glucocorticoid114752057 +
, http://www.wikidata.org/entity/Q8386 +
, http://dbpedia.org/class/yago/Corticosteroid114751417 +
, http://dbpedia.org/class/yago/WikicatGlucocorticoids +
, http://dbpedia.org/class/yago/Part113809207 +
, http://dbpedia.org/class/yago/Matter100020827 +
, http://dbpedia.org/class/yago/Substance100019613 +
, http://dbpedia.org/class/yago/Abstraction100002137 +
, http://dbpedia.org/ontology/Drug +
, http://dbpedia.org/class/yago/BodySubstance105263850 +
, http://dbpedia.org/class/yago/Secretion105404728 +
, http://dbpedia.org/ontology/ChemicalSubstance +
, http://dbpedia.org/class/yago/WikicatCorticosteroids +
, http://dbpedia.org/class/yago/Hormone105407119 +
, http://dbpedia.org/class/yago/SteroidHormone114745635 +
, http://dbpedia.org/class/yago/LiquidBodySubstance105397468 +
, http://dbpedia.org/class/yago/Message106598915 +
, http://dbpedia.org/class/yago/PhysicalEntity100001930 +
, http://umbel.org/umbel/rc/DrugProduct +
, http://dbpedia.org/class/yago/Relation100031921 +
, http://dbpedia.org/class/yago/WikicatMolecularFormulas +
, http://dbpedia.org/class/yago/MolecularFormula106817173 +
, http://dbpedia.org/class/yago/Formula106816935 +
, http://dbpedia.org/class/yago/Statement106722453 +
, http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#ChemicalObject +
|
| rdfs:comment |
Il fluocinolone acetonide è un corticosteroide, derivato sintetico dell'idrocortisone, utilizzato in particolare in dermatologia per ridurre un processo infiammatorio a livello della pelle.
, Флуоцинолона ацетонид (Fluocinolone aceton … Флуоцинолона ацетонид (Fluocinolone acetonide) — противовоспалительное лекарственное средство, глюкокортикостероид, применяется в виде мази для наружного применения. Выпускается под наименованиями«Синафлан», «Флуцинар», «Синалар», «Синодерм», «Флукорт», «Эзацинон».налар», «Синодерм», «Флукорт», «Эзацинон».
, Fluocynolon – organiczny związek chemiczny … Fluocynolon – organiczny związek chemiczny, syntetyczny, fluorowany steroidowy lek przeciwzapalny i przeciwuczuleniowy. Zmniejsza obrzęk oraz przepuszczalność naczyń włosowatych. Siła działania przeciwzapalnego, przeciwuczuleniowego i kurczącego naczynia krwionośne jest porównywalna z triamcynolonem.onośne jest porównywalna z triamcynolonem.
, Fluocinolone acetonide is a corticosteroid … Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocortisone derivative. The fluorine substitution at position 9 in the steroid nucleus greatly enhances its activity. It was first synthesized in 1959 in the Research Department of Syntex Laboratories S.A. Mexico City. Preparations containing it were first marketed under the name Synalar. A typical dosage strength used in dermatology is 0.01–0.025%. One such cream is sold under the brand name Flucort-N and includes the antibiotic neomycin.rt-N and includes the antibiotic neomycin.
, Fluocinolona acetonida é um corticosteroid … Fluocinolona acetonida é um corticosteroide primariamente usado em dermatologia para reduzir inflamação da pele e aliviar coceiras. É uma derivado sintético da hidrocortisona. A substituição de flúor na posição 9 no núcleo de esteróides aumenta grandemente a sua atividade. Foi sintetizado pela primeira vez em 1959 no Departamento de Pesquisa da Syntex Laboratories S.A, Cidade do México City. Preparações que o continham foram comercializados pela primeira vez sob o nome Synalar. Uma dosagem típica utilizada em dermatologia é 0,01–0,025%. Um desses cremes é vendido sob a marca Flucort-N e inclui o antibiótico neomicina.lucort-N e inclui o antibiótico neomicina.
, 醋酸氟轻松（英文：Fluocinolone acetonide）是一种皮质类固醇，主要用于治疗皮肤病，减少皮肤炎症和缓解瘙痒。 它是合成的氢化可的松衍生物。类固醇核中第9位的氟取代大大增强了它的活性。它于1959年在墨西哥城Syntex实验室研究部门首次合成。含有醋酸氟轻松的药膏最初以仙乃乐（Synalar）的注册商标进行销售。治疗皮肤病的药膏中使用的氟轻松的典型剂量为0.01-0.025％。但氟轻松作为一种外用類固醇藥物不能殺菌，反而會助長細菌滋生，所以不能用於感染性皮膚病，例如癬和疥瘡。
, Acetónido de fluocinolona es un corticoste … Acetónido de fluocinolona es un corticosteroide potente de grado III, empleado fundamentalmente en dermatología para reducir la inflamación de la piel y reducir el prurito o picor. Es un derivado sintético de hidrocortisona y fue sintetizado por primera vez en 1959 en el departamento de investigación de Syntex Laboratories S.A. de Ciudad de México. El átomo de flúor sustituido en la posición 9 del núcleo esteroide aumenta su actividad. La dosis típica usada en dermatología es 0.01–0.025%.[cita requerida]rmatología es 0.01–0.025%.[cita requerida]
|
| rdfs:label |
Fluocinolone acetonide
, 醋酸氟轻松
, Acetónido de fluocinolona
, Acetònid de fluocinolona
, Fluocynolon
, Флуоцинолона ацетонид
, Fluocinolona acetonida
|
