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L'Arxiu Europeu de Nucleòtids (European Nu … L'Arxiu Europeu de Nucleòtids (European Nucleotide Archive, ENA) és un dipòsit que proporciona accés gratuït i sense restriccions a seqüències anotades d’ADN i ARN. A més, emmagatzema informació complementària, com ara procediments experimentals, detalls del muntatge de seqüències i altres dades relacionades amb projectes de seqüenciació. L’ENA va ser creat i és mantingut per l'Institut Europeu de Bioinformàtica i és membre de la International Nucleotide Sequence Database Collaboration (INSDC) juntament amb el DNA DataBank del Japó (DDBJ) i GenBank. ENA es va establir a principis dels anys vuitanta com a EMBL Data Library (més tard rebatejada com EMBL Nucleotide Sequence Database, EMBL-Bank) i es va centrar inicialment en seqüències de nucleòtids altament anotades. L'arxiu consisteix en nivells d’anotació ENA, ensamblatge ENA i ENA-Reads. A l'octubre de 2009, ENA-Annotation i ENA-Assembly contenien 163 milions de registres que corresponien a 283.000 milions de bases. Les seqüències obtingudes "per perdigonada" (shotgun) de genoma complet continuen sent la font dominant de noves seqüències (un 30% de seqüències i un 53% de bases) seguides de les de marcadors de seqüència expressada (EST) (38% de seqüències i 12% de bases). (EST) (38% de seqüències i 12% de bases).
, Das European Nucleotide Archive (Europäisc … Das European Nucleotide Archive (Europäisches Nukleotid-Archiv; ENA) ist eine der drei großen internationalen Datenbanken über Nukleotidsequenzen. Sie umfasst die EMBL Nucleotide Sequence Database (EMBL-Bank), vormals EMBL Data Library, sowie weitere Datenquellen. Das ENA wird vom Europäischen Bioinformatik-Institute (EBI) gepflegt und bereitgestellt. Gegründet wurde sie 1980 am Europäischen Laboratorium for Molekularbiologie (EMBL) in Heidelberg. Nach Ausgründung des EBI als EMBL-Außenstelle in Hinxton bei Cambridge, UK, übernahm dieses die Weiterführung der Datenbank. Die EMBL-Bank ist Europas primäres Archiv für Nukleotidsequenzen (DNA- und RNA-Sequenzen). Hauptquelle für ihre Inhalte sind Direkteinreichungen durch die Forscher, die diese Sequenzen bestimmt haben. Die meisten wissenschaftlichen Zeitschriften verlangen einen Nachweis über die Einreichung bei der EMBL-Bank oder einer der Partnerdatenbanken (s. INSDC), bevor sie ein Manuskript mit einer neuen Nukleotidsequenz zur Veröffentlichung annehmen. Release 106 vom Dezember 2010 umfasst nahezu 200 Millionen Einträge. Der Zugang zur EMBL-Bank ist frei und online oder über downloads möglich.ei und online oder über downloads möglich.
, The European Nucleotide Archive (ENA) is a … The European Nucleotide Archive (ENA) is a repository providing free and unrestricted access to annotated DNA and RNA sequences. It also stores complementary information such as experimental procedures, details of sequence assembly and other metadata related to sequencing projects.The archive is composed of three main databases: the Sequence Read Archive, the Trace Archive and the EMBL Nucleotide Sequence Database (also known as EMBL-bank). The ENA is produced and maintained by the European Bioinformatics Institute and is a member of the International Nucleotide Sequence Database Collaboration (INSDC) along with the DNA Data Bank of Japan and GenBank. The ENA has grown out of the EMBL Data Library which was released in 1982 as the first internationally supported resource for nucleotide sequence data. As of early 2012, the ENA and other INSDC member databases each contained complete genomes of 5,682 organisms and sequence data for almost 700,000.Moreover, the volume of data is increasing exponentially with a doubling time of approximately 10 months. doubling time of approximately 10 months.
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Das European Nucleotide Archive (Europäisc … Das European Nucleotide Archive (Europäisches Nukleotid-Archiv; ENA) ist eine der drei großen internationalen Datenbanken über Nukleotidsequenzen. Sie umfasst die EMBL Nucleotide Sequence Database (EMBL-Bank), vormals EMBL Data Library, sowie weitere Datenquellen. Das ENA wird vom Europäischen Bioinformatik-Institute (EBI) gepflegt und bereitgestellt. Gegründet wurde sie 1980 am Europäischen Laboratorium for Molekularbiologie (EMBL) in Heidelberg. Nach Ausgründung des EBI als EMBL-Außenstelle in Hinxton bei Cambridge, UK, übernahm dieses die Weiterführung der Datenbank.hm dieses die Weiterführung der Datenbank.
, The European Nucleotide Archive (ENA) is a … The European Nucleotide Archive (ENA) is a repository providing free and unrestricted access to annotated DNA and RNA sequences. It also stores complementary information such as experimental procedures, details of sequence assembly and other metadata related to sequencing projects.The archive is composed of three main databases: the Sequence Read Archive, the Trace Archive and the EMBL Nucleotide Sequence Database (also known as EMBL-bank). The ENA is produced and maintained by the European Bioinformatics Institute and is a member of the International Nucleotide Sequence Database Collaboration (INSDC) along with the DNA Data Bank of Japan and GenBank.th the DNA Data Bank of Japan and GenBank.
, L'Arxiu Europeu de Nucleòtids (European Nu … L'Arxiu Europeu de Nucleòtids (European Nucleotide Archive, ENA) és un dipòsit que proporciona accés gratuït i sense restriccions a seqüències anotades d’ADN i ARN. A més, emmagatzema informació complementària, com ara procediments experimentals, detalls del muntatge de seqüències i altres dades relacionades amb projectes de seqüenciació.elacionades amb projectes de seqüenciació.
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European Nucleotide Archive
, Arxiu Europeu de Nucleòtids
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