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Erythropoiesis-stimulating agents (ESA) ar … Erythropoiesis-stimulating agents (ESA) are medications which stimulate the bone marrow to make red blood cells. They are used to treat anemia due to end stage kidney disease, chemotherapy, major surgery, or certain treatments in HIV/AIDS. In these situations they decrease the need for blood transfusions. The different agents are more or less equivalent. They are given by injection. Common side effects may include joint pain, rash, vomiting, and headache. Serious side effects may include heart attacks, stroke, increased cancer growth, or pure red cell aplasia. It is unclear if use is safe during pregnancy. They work similar to naturally occurring erythropoietin. They were first approved for medical use in the United States in 1989. It is on the World Health Organization's List of Essential Medicines. Commercially available agents include epoetin alfa and darbepoetin alfa, and biosimilars. Use among athletes is prohibited by the World Anti-Doping Agency.rohibited by the World Anti-Doping Agency.
, Un agente estimulante de la eritropoyesis … Un agente estimulante de la eritropoyesis (del inglés erythropoiesis-stimulating agent), abreviado ESA, es un agente similar a la citocina eritropoyetina, que estimula la eritropoyesis, proceso encargado de la producción de eritrocitos. Los ESAs son parecidos a la proteína natural eritropoyetina tanto en la estructura química como en los procesos biológicos en que participan.los procesos biológicos en que participan.
, Agen Stimulan Eritropoiesis (ASE) adalah m … Agen Stimulan Eritropoiesis (ASE) adalah medikasi yang memicu sumsum tulang agar . Bahan ini dipakai dalam pengobatan anemia karena penyakit ginjal stadium akhir, kemoterapi, pembedahan besar, atau penanganan tertentu HIV/AIDS. Dalam kondisi ini, kebutuhan transfusi darah menurun. Bahan-bahan yang berbeda kurang lebih sama. Pemberian dilakukan dengan suntikan. Efek samping yang umum meliputi , , muntah, dan sakit kepala. Efek samping berat mencakup serangan jantung, stroke, peningkatan pertumbuhan kanker, atau . Keamananan konsumsi selama kehamilan belum jelas. Kerja bahan ini serupa dengan eritropoietin yang ada secara alami. ASE pertama kali disetujui penggunaan kesehatannya di Amerika Serikat pada 1989. Bahan ini termasuk dalam Daftar Obat Esensial Organisasi Kesehatan Dunia, yang menyebutkan obat paling efektif dan aman yang dibutuhkan dalam . Bahan yang tersedia secara komersial termasuk dan , dan juga . Harga grosir satu versi di negara berkembang, pada 2015, adalah sekitar 3,80 USD per 2000 unit vial. Di Inggris, jumlah yang sama dihargai sekitar 10 pound pada 2015. Penggunaan dalam dunia atlet dilarang oleh World Anti-Doping Agency.et dilarang oleh World Anti-Doping Agency.
, عوامل محفزة لتكوين كريات الدم الحمراء أو م … عوامل محفزة لتكوين كريات الدم الحمراء أو منشطات هرمون الإريثروبويتين (بالإنجليزية: Erythropoiesis-stimulating agent) اختصاراً (ESA) هي الأدوية التي تحفز نخاع العظم على تكوين خلايا الدم الحمراء. يتم استخدامها لعلاج فقر الدم المرتبط بأمراض الكلى المزمنة، أو المرتبط بالعلاج الكيميائي، أو العمليات الجراحية الكبيرة، أو بعض علاجات فيروس نقص المناعة البشرية. وبهذه الطريقة تقل الحاجة إلى عمليات نقل الدم. يتم إعطاءها عن طريق الحقن.مليات نقل الدم. يتم إعطاءها عن طريق الحقن.
, Erythropoiesis-Stimulating Agents (kurz: E … Erythropoiesis-Stimulating Agents (kurz: ESA, zu Deutsch: Erythropoese-stimulierende Substanzen), sind Substanzen, welche die Bildung roter Blutkörperchen (Erythrozyten) anregen (siehe Erythropoese). Zu dieser Substanzgruppe gehören einige natürlich vorkommende Wachstumsfaktoren (Zytokine) wie z. B. die Interleukine IL-3 und IL-9. Das wohl bekannteste ESA ist das Hormon Erythropoetin. Im Zuge der Entwicklung von Medikamenten, welche die blutbildenden Eigenschaften des Erythropoetin nachahmen, wurden zahlreiche ESA mit Hilfe von molekularbiologischen und biotechnologischen Verfahren künstlich hergestellt (siehe EPO-Präparate der nächsten Generation).he EPO-Präparate der nächsten Generation).
, Agentes estimulantes de eritropoiese (ESA) … Agentes estimulantes de eritropoiese (ESA) são medicamentos que estimulam a medula óssea para fazer as células vermelhas do sangue. Eles são usados para tratar a anemia, devido à fase final da doença renal, quimioterapia, cirurgia de grande porte, ou em determinados tratamentos de VIH/SIDA. Em uma dessas situações, eles diminuem a necessidade de transfusões de sangue. Os diferentes agentes são mais ou menos equivalentes. Eles são administrados através de injecção. Efeitos secundários frequentes podem incluir dor nas articulações, erupção cutânea, vómitos e dor de cabeça. Graves efeitos secundários podem incluir ataques cardíacos, acidente vascular cerebral ou aumento do ritmo de crescimento de um cancro. Não está claro se o uso é seguro durante a gravidez. Estes medicamentos trabalham de maneira semelhante à eritropoietina. Eles foram aprovados para uso médico nos Estados Unidos, em 1989. Fazem parte da Lista de Medicamentos Essenciais da Organização Mundial de Saúde, uma lista dos mais eficazes e seguros medicamentos que são necessários em um sistema de saúde. Agentes disponíveis comercialmente incluem alfaepoetina e darbepoetina alfa, bem como os biosimilares. O custo de uma versão destes medicamentos no mundo em desenvolvimento, em 2015, foi de cerca de 3.80 USD por 2000 unidades em frasco. No Reino Unido, esta quantidade custa o equivalente a cerca de 10 quilos de 2015. Entre os atletas é proibido pela Agência Mundial Anti-Doping.proibido pela Agência Mundial Anti-Doping.
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Erythropoiesis-Stimulating Agents (kurz: E … Erythropoiesis-Stimulating Agents (kurz: ESA, zu Deutsch: Erythropoese-stimulierende Substanzen), sind Substanzen, welche die Bildung roter Blutkörperchen (Erythrozyten) anregen (siehe Erythropoese). Zu dieser Substanzgruppe gehören einige natürlich vorkommende Wachstumsfaktoren (Zytokine) wie z. B. die Interleukine IL-3 und IL-9. wie z. B. die Interleukine IL-3 und IL-9.
, عوامل محفزة لتكوين كريات الدم الحمراء أو م … عوامل محفزة لتكوين كريات الدم الحمراء أو منشطات هرمون الإريثروبويتين (بالإنجليزية: Erythropoiesis-stimulating agent) اختصاراً (ESA) هي الأدوية التي تحفز نخاع العظم على تكوين خلايا الدم الحمراء. يتم استخدامها لعلاج فقر الدم المرتبط بأمراض الكلى المزمنة، أو المرتبط بالعلاج الكيميائي، أو العمليات الجراحية الكبيرة، أو بعض علاجات فيروس نقص المناعة البشرية. وبهذه الطريقة تقل الحاجة إلى عمليات نقل الدم. يتم إعطاءها عن طريق الحقن.مليات نقل الدم. يتم إعطاءها عن طريق الحقن.
, Agen Stimulan Eritropoiesis (ASE) adalah m … Agen Stimulan Eritropoiesis (ASE) adalah medikasi yang memicu sumsum tulang agar . Bahan ini dipakai dalam pengobatan anemia karena penyakit ginjal stadium akhir, kemoterapi, pembedahan besar, atau penanganan tertentu HIV/AIDS. Dalam kondisi ini, kebutuhan transfusi darah menurun. Bahan-bahan yang berbeda kurang lebih sama. Pemberian dilakukan dengan suntikan.sama. Pemberian dilakukan dengan suntikan.
, Agentes estimulantes de eritropoiese (ESA) … Agentes estimulantes de eritropoiese (ESA) são medicamentos que estimulam a medula óssea para fazer as células vermelhas do sangue. Eles são usados para tratar a anemia, devido à fase final da doença renal, quimioterapia, cirurgia de grande porte, ou em determinados tratamentos de VIH/SIDA. Em uma dessas situações, eles diminuem a necessidade de transfusões de sangue. Os diferentes agentes são mais ou menos equivalentes. Eles são administrados através de injecção.les são administrados através de injecção.
, Erythropoiesis-stimulating agents (ESA) ar … Erythropoiesis-stimulating agents (ESA) are medications which stimulate the bone marrow to make red blood cells. They are used to treat anemia due to end stage kidney disease, chemotherapy, major surgery, or certain treatments in HIV/AIDS. In these situations they decrease the need for blood transfusions. The different agents are more or less equivalent. They are given by injection.s equivalent. They are given by injection.
, Un agente estimulante de la eritropoyesis … Un agente estimulante de la eritropoyesis (del inglés erythropoiesis-stimulating agent), abreviado ESA, es un agente similar a la citocina eritropoyetina, que estimula la eritropoyesis, proceso encargado de la producción de eritrocitos. Los ESAs son parecidos a la proteína natural eritropoyetina tanto en la estructura química como en los procesos biológicos en que participan.los procesos biológicos en que participan.
|
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Agen Stimulan Eritropoiesis
, عامل محفز لتكون الكريات الحمر
, Agente estimulador de la eritropoyesis
, Erythropoiesis-stimulating agent
, Agente estimulante de eritropoiese
, Erythropoiesis-Stimulating Agent
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