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5α-Dihydrodeoxycorticosterone (abbreviated … 5α-Dihydrodeoxycorticosterone (abbreviated as DHDOC), also known as 21-hydroxy-5α-pregnan-20-one, is an endogenous progestogen and neurosteroid. It is synthesized from the adrenal hormone deoxycorticosterone (DOC) by the enzyme 5α-reductase type I. DHDOC is an agonist of the progesterone receptor, as well as a positive allosteric modulator of the GABAA receptor, and is known to have anticonvulsant effects.d is known to have anticonvulsant effects.
, Дигидродеоксикортикостерон (5α-дигидродезо … Дигидродеоксикортикостерон (5α-дигидродезоксикортикостерон, 5α-ДГДОКС, 21-гидрокси-5α-прегнан-20-он) — минералокортикоидный стероидным гормоном, нейростероид. Синтезируется из гормона надпочечников деоксикортикостерона (ДОКС) ферментом 5α-редуктаза типа I. ДГДОКС является агонистом прогестогенового рецептора, а также положительным аллостерическим модулятором рецептора ГАМКА и, как известно, оказывает противосудорожное действие.тно, оказывает противосудорожное действие.
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5α-Dihydro-11-deoxycorticosterone
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(1S,3aS,3bR,5aS,9aS,9bS,11aS)-1-(Hydroxyacetyl)-9a,11a-dimethylhexadecahydro-7H-cyclopenta[a]phenanthren-7-one
, 21-Hydroxy-5α-pregnane-3,20-dione
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5α-Dihydrodeoxycorticosterone (abbreviated … 5α-Dihydrodeoxycorticosterone (abbreviated as DHDOC), also known as 21-hydroxy-5α-pregnan-20-one, is an endogenous progestogen and neurosteroid. It is synthesized from the adrenal hormone deoxycorticosterone (DOC) by the enzyme 5α-reductase type I. DHDOC is an agonist of the progesterone receptor, as well as a positive allosteric modulator of the GABAA receptor, and is known to have anticonvulsant effects.d is known to have anticonvulsant effects.
, Дигидродеоксикортикостерон (5α-дигидродезо … Дигидродеоксикортикостерон (5α-дигидродезоксикортикостерон, 5α-ДГДОКС, 21-гидрокси-5α-прегнан-20-он) — минералокортикоидный стероидным гормоном, нейростероид. Синтезируется из гормона надпочечников деоксикортикостерона (ДОКС) ферментом 5α-редуктаза типа I. ДГДОКС является агонистом прогестогенового рецептора, а также положительным аллостерическим модулятором рецептора ГАМКА и, как известно, оказывает противосудорожное действие.тно, оказывает противосудорожное действие.
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Дигидродеоксикортикостерон
, Dihydrodeoxycorticosterone
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