| http://dbpedia.org/ontology/abstract
|
CRAL-TRIO domain is a protein structural d … CRAL-TRIO domain is a protein structural domain that binds small lipophilic molecules. This domain is named after cellular retinaldehyde-binding protein (CRALBP) and TRIO guanine exchange factor. CRALB protein carries 11-cis-retinol or 11-cis-retinaldehyde. It modulates interaction of retinoids with visual cycle enzymes. TRIO is involved in coordinating actin remodeling, which is necessary for cell migration and growth. Other members of the family are alpha-tocopherol transfer protein and phosphatidylinositol-transfer protein (Sec14). They transport their substrates (alpha-tocopherol and phosphatidylinositol or phosphatidylcholine, respectively) between different intracellular membranes. Family also include a guanine nucleotide exchange factor that may function as an effector of RAC1 small G-protein. The N-terminal domain of yeast ECM25 protein has been identified as containing a lipid binding CRAL-TRIO domain.ntaining a lipid binding CRAL-TRIO domain.
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| http://dbpedia.org/ontology/symbol
|
CRAL_TRIO
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| http://dbpedia.org/ontology/thumbnail
|
http://commons.wikimedia.org/wiki/Special:FilePath/1r5l_opm.png?width=300 +
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| http://dbpedia.org/ontology/wikiPageID
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9321146
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| http://dbpedia.org/ontology/wikiPageLength
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3685
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| http://dbpedia.org/ontology/wikiPageRevisionID
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1040147828
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| http://dbpedia.org/ontology/wikiPageWikiLink
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http://dbpedia.org/resource/Rac1 +
, http://dbpedia.org/resource/SEC14L2 +
, http://dbpedia.org/resource/Sec14 +
, http://dbpedia.org/resource/MOSPD2 +
, http://dbpedia.org/resource/PTPN9 +
, http://dbpedia.org/resource/G-protein +
, http://dbpedia.org/resource/RLBP1 +
, http://dbpedia.org/resource/Retinol +
, http://dbpedia.org/resource/TTPA +
, http://dbpedia.org/resource/Lipid +
, http://dbpedia.org/resource/TRIO_%28gene%29 +
, http://dbpedia.org/resource/Category:Peripheral_membrane_proteins +
, http://dbpedia.org/resource/Tocopherol +
, http://dbpedia.org/resource/Alpha_helix +
, http://dbpedia.org/resource/Beta_sheet +
, http://dbpedia.org/resource/Phosphatidylcholine +
, http://dbpedia.org/resource/RLBP1L2 +
, http://dbpedia.org/resource/SEC14L3 +
, http://dbpedia.org/resource/C20orf121 +
, http://dbpedia.org/resource/Category:Water-soluble_transporters +
, http://dbpedia.org/resource/RLBP1L1 +
, http://dbpedia.org/resource/Retinaldehyde-binding_protein_1 +
, http://dbpedia.org/resource/Actin_remodeling +
, http://dbpedia.org/resource/Category:Protein_domains +
, http://dbpedia.org/resource/SEC14L4 +
, http://dbpedia.org/resource/Nucleotide_exchange_factor +
, http://dbpedia.org/resource/Structural_domain +
, http://dbpedia.org/resource/Alpha-tocopherol +
, http://dbpedia.org/resource/SEC14L1 +
, http://dbpedia.org/resource/Phosphatidylinositol +
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| http://dbpedia.org/property/caption
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Alpha-tocopherol transfer protein, closed state with ligand.
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| http://dbpedia.org/property/cdd
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cd00170
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| http://dbpedia.org/property/interpro
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IPR001251
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| http://dbpedia.org/property/membranomeSuperfamily
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576
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| http://dbpedia.org/property/name
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CRAL/TRIO domain
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| http://dbpedia.org/property/opmFamily
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121
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| http://dbpedia.org/property/opmProtein
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1
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| http://dbpedia.org/property/pfam
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PF00650
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| http://dbpedia.org/property/scop
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1
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| http://dbpedia.org/property/smart
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Sec14
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| http://dbpedia.org/property/symbol
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CRAL_TRIO
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| http://dbpedia.org/property/width
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200
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| http://dbpedia.org/property/wikiPageUsesTemplate
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http://dbpedia.org/resource/Template:Reflist +
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| http://purl.org/dc/terms/subject
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http://dbpedia.org/resource/Category:Protein_domains +
, http://dbpedia.org/resource/Category:Water-soluble_transporters +
, http://dbpedia.org/resource/Category:Peripheral_membrane_proteins +
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| http://purl.org/linguistics/gold/hypernym
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http://dbpedia.org/resource/Domain +
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| http://www.w3.org/ns/prov#wasDerivedFrom
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http://en.wikipedia.org/wiki/CRAL-TRIO_domain?oldid=1040147828&ns=0 +
|
| http://xmlns.com/foaf/0.1/depiction
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http://commons.wikimedia.org/wiki/Special:FilePath/1r5l_opm.png +
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http://en.wikipedia.org/wiki/CRAL-TRIO_domain +
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|
| rdfs:comment |
CRAL-TRIO domain is a protein structural d … CRAL-TRIO domain is a protein structural domain that binds small lipophilic molecules. This domain is named after cellular retinaldehyde-binding protein (CRALBP) and TRIO guanine exchange factor. CRALB protein carries 11-cis-retinol or 11-cis-retinaldehyde. It modulates interaction of retinoids with visual cycle enzymes. TRIO is involved in coordinating actin remodeling, which is necessary for cell migration and growth. The N-terminal domain of yeast ECM25 protein has been identified as containing a lipid binding CRAL-TRIO domain.ntaining a lipid binding CRAL-TRIO domain.
|
| rdfs:label |
CRAL-TRIO domain
|
