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Bisoctrizole (INN/USAN, marketed by BASF a … Bisoctrizole (INN/USAN, marketed by BASF as Tinosorb M, by DSM Nutritional Products as Parsol Max , by Everlight Chemical as Eversorb M, and by MPI as Milestab 360, INCI methylene bis-benzotriazolyl tetramethylbutylphenol) is a phenolic benzotriazole that is added to sunscreens to absorb UV rays. It is a broad-spectrum ultraviolet radiation absorber, absorbing UVB as well as UVA rays. It also reflects and scatters UV. Bisoctrizole is what is termed is a hybrid UV absorber, which has been described as an organic UV filter produced in microfine organic particles (< 200 nm), like microfine zinc oxide and titanium dioxide. Where other organic UV absorbers dissolved in either the oily or aqueous phases, bisoctrizole dissolves poorly in both. Hence, bisoctrizole is formulated in sunscreen preparations as a 50% suspension, the absorber added to the water phase, and mineral micropigments usually added to the oil phase. The bisoctrizole particles are stabilized by the surfactant decyl glucoside. The compound shows very little photodegradation, and has a stabilizing effect on other UV absorbers, octyl methoxycinnamate (octinoxate) in particular. In primary research reports, bisoctrizole has been reported to minimally penetrate skin, and has been described as lacking estrogenic effects in vitro. As of this date, bisoctrizole had not been approved by the U.S. Food and Drug Administration (FDA), but is approved in the EU and other parts of the world.ed in the EU and other parts of the world.
, Bisoctrizol (Handelsnamen: Tinosorb M, Mil … Bisoctrizol (Handelsnamen: Tinosorb M, Milestab 360) ist eine chemische Verbindung aus der Gruppe der 2-(2-Hydroxyphenyl)-2H-benzotriazole, die als UV-Stabilisator verwendet wird. Sie kommt nicht natürlich vor. Formal ist Bisoctrizol ist das über eine Methylengruppe verknüpfte Dimer von Octrizol.hylengruppe verknüpfte Dimer von Octrizol.
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2,2′-Methylenebis[6-(2H-1,2,3-benzotriazol-2-yl)-4-(2,4,4-trimethylpentan-2-yl)phenol]
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Space-filling model of the bisoctrizole molecule
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| rdfs:comment |
Bisoctrizole (INN/USAN, marketed by BASF a … Bisoctrizole (INN/USAN, marketed by BASF as Tinosorb M, by DSM Nutritional Products as Parsol Max , by Everlight Chemical as Eversorb M, and by MPI as Milestab 360, INCI methylene bis-benzotriazolyl tetramethylbutylphenol) is a phenolic benzotriazole that is added to sunscreens to absorb UV rays. It is a broad-spectrum ultraviolet radiation absorber, absorbing UVB as well as UVA rays. It also reflects and scatters UV. In primary research reports, bisoctrizole has been reported to minimally penetrate skin, and has been described as lacking estrogenic effects in vitro.ed as lacking estrogenic effects in vitro.
, Bisoctrizol (Handelsnamen: Tinosorb M, Mil … Bisoctrizol (Handelsnamen: Tinosorb M, Milestab 360) ist eine chemische Verbindung aus der Gruppe der 2-(2-Hydroxyphenyl)-2H-benzotriazole, die als UV-Stabilisator verwendet wird. Sie kommt nicht natürlich vor. Formal ist Bisoctrizol ist das über eine Methylengruppe verknüpfte Dimer von Octrizol.hylengruppe verknüpfte Dimer von Octrizol.
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Bisoctrizole
, Bisoctrizol
|
