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Ampakines, also stylized as AMPAkines, are … Ampakines, also stylized as AMPAkines, are a subgroup of AMPA receptor positive allosteric modulators with a benzamide or closely related chemical structure. They are also known as "CX compounds". Ampakines take their name from the AMPA receptor (AMPAR), a type of ionotropic glutamate receptor with which the ampakines interact and act as positive allosteric modulators (PAMs) of. Although all ampakines are AMPAR PAMs, not all AMPAR PAMs are ampakines. They are currently being investigated as potential treatment for a range of conditions involving mental disability and disturbances such as Alzheimer's disease, Parkinson's disease, schizophrenia, treatment-resistant depression (TRD) or neurological disorders such as attention deficit hyperactivity disorder (ADHD), among others. More recently developed ampakine compounds are much more potent and selective for the AMPA receptor target, and while none of the newer selective ampakine compounds have yet come onto the market, various ampakines are in clinical trials. various ampakines are in clinical trials.
, Ampaquinas são uma classe de compostos car … Ampaquinas são uma classe de compostos caracterizados por aumentar o limiar de atenção e o estado de alerta, e também por facilitar a aprendizagem e memória. A denominação ampaquina é derivada do de ácido glutâmico, com os quais interagem fortemente. O receptor Ampa, por sua vez, tirou seu nome do composto , que se liga ao receptor de maneira seletiva A DARPA é uma das instituições que investigam as ampaquinas. Nesse caso, as pesquisas estão direcionadas para obter aplicações que aprimorem o desempenho militar de humanos.aprimorem o desempenho militar de humanos.
, Les ampakines sont une classe de composés … Les ampakines sont une classe de composés connus pour augmenter la capacité d'attention et de vigilance et pour faciliter l'apprentissage et la mémoire. Les ampakines tirent leur nom des récepteurs AMPA glutamatergiques avec lesquels elles interagissent fortement. Les récepteurs AMPA tirent eux-mêmes leur nom de l'acronyme AMPA, du nom anglais de l'acide 2-amino-3-(5-méthyl-3-hydroxy-1,2-oxazol-4-yl)propanoïque (2-Amino-3-(5-Methyl-3-oxo-1,2-oxazol-4-yl)Propanoic Acid), qui se lie sélectivement à eux. Les ampakines ont été étudiées par la DARPA (Defense Advanced Research Projects Agency) américaine pour une utilisation potentielle chez les militaires.ilisation potentielle chez les militaires.
, Ампакины (англ. ampakines) — новый класс н … Ампакины (англ. ampakines) — новый класс ноотропных препаратов, способствующих мозговой активности для увеличения внимания, бдительности, повышения обучаемости и улучшения памяти. Ампакины получили название от ионотропного глутаматного AMPA-рецептора нейронов, с которым они сильно взаимодействуют. В свою очередь, AMPA-рецептор был назван по селективно связывающейся с ним альфа-аминометилизоксазолпропионовой кислоте (АМРА).ометилизоксазолпропионовой кислоте (АМРА).
, Las ampakinas (también denominadas ampaqui … Las ampakinas (también denominadas ampaquinas o AMPAkinas) son una clase de compuestos nootropos conocidos por mejorar la capacidad de atención y alerta, y facilitar el aprendizaje y la memoria. Las ampaquinas toman su nombre del receptor glutamatérgico AMPA, con el que interactúan fuertemente. El receptor AMPA, a su vez, recibe su nombre de AMPA, que se une selectivamente a la misma.A, que se une selectivamente a la misma.
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Ampaquinas são uma classe de compostos car … Ampaquinas são uma classe de compostos caracterizados por aumentar o limiar de atenção e o estado de alerta, e também por facilitar a aprendizagem e memória. A denominação ampaquina é derivada do de ácido glutâmico, com os quais interagem fortemente. O receptor Ampa, por sua vez, tirou seu nome do composto , que se liga ao receptor de maneira seletiva A DARPA é uma das instituições que investigam as ampaquinas. Nesse caso, as pesquisas estão direcionadas para obter aplicações que aprimorem o desempenho militar de humanos.aprimorem o desempenho militar de humanos.
, Les ampakines sont une classe de composés … Les ampakines sont une classe de composés connus pour augmenter la capacité d'attention et de vigilance et pour faciliter l'apprentissage et la mémoire. Les ampakines tirent leur nom des récepteurs AMPA glutamatergiques avec lesquels elles interagissent fortement. Les récepteurs AMPA tirent eux-mêmes leur nom de l'acronyme AMPA, du nom anglais de l'acide 2-amino-3-(5-méthyl-3-hydroxy-1,2-oxazol-4-yl)propanoïque (2-Amino-3-(5-Methyl-3-oxo-1,2-oxazol-4-yl)Propanoic Acid), qui se lie sélectivement à eux.oic Acid), qui se lie sélectivement à eux.
, Las ampakinas (también denominadas ampaqui … Las ampakinas (también denominadas ampaquinas o AMPAkinas) son una clase de compuestos nootropos conocidos por mejorar la capacidad de atención y alerta, y facilitar el aprendizaje y la memoria. Las ampaquinas toman su nombre del receptor glutamatérgico AMPA, con el que interactúan fuertemente. El receptor AMPA, a su vez, recibe su nombre de AMPA, que se une selectivamente a la misma.A, que se une selectivamente a la misma.
, Ампакины (англ. ampakines) — новый класс н … Ампакины (англ. ampakines) — новый класс ноотропных препаратов, способствующих мозговой активности для увеличения внимания, бдительности, повышения обучаемости и улучшения памяти. Ампакины получили название от ионотропного глутаматного AMPA-рецептора нейронов, с которым они сильно взаимодействуют. В свою очередь, AMPA-рецептор был назван по селективно связывающейся с ним альфа-аминометилизоксазолпропионовой кислоте (АМРА).ометилизоксазолпропионовой кислоте (АМРА).
, Ampakines, also stylized as AMPAkines, are … Ampakines, also stylized as AMPAkines, are a subgroup of AMPA receptor positive allosteric modulators with a benzamide or closely related chemical structure. They are also known as "CX compounds". Ampakines take their name from the AMPA receptor (AMPAR), a type of ionotropic glutamate receptor with which the ampakines interact and act as positive allosteric modulators (PAMs) of. Although all ampakines are AMPAR PAMs, not all AMPAR PAMs are ampakines.AR PAMs, not all AMPAR PAMs are ampakines.
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Ampakine
, Ampakina
, Ампакины
, Ampaquina
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