| http://dbpedia.org/ontology/abstract
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The ANTH domain is a membrane binding doma … The ANTH domain is a membrane binding domain that shows weak specificity for PtdIns(4,5)P2. It was found in AP180 (homologous to CALM) endocytotic accessory protein that has been implicated in the formation of clathrin-coated pits. The domain is involved in phosphatidylinositol 4,5-bisphosphate binding and is a universal adaptor for nucleation of clathrin coats. Its structure is a solenoid of 9 helices. The PtdIns(4,5)P2 binding residues are spread over several helices at the tip of the structure. The PtdIns(4,5)P2 binding sequence is Kx9Kx(K/R)(H/Y). An ANTH domain is also found in HIP1 and HIP1R, and the PtdIns(4,5)P2 binding sequence is conserved. More information is found on endocytosis.org.e information is found on endocytosis.org.
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| http://dbpedia.org/ontology/symbol
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ANTH
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| http://dbpedia.org/ontology/thumbnail
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http://commons.wikimedia.org/wiki/Special:FilePath/1hfa_opm.png?width=300 +
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| http://dbpedia.org/ontology/wikiPageExternalLink
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https://web.archive.org/web/20070313235047/http:/www.endocytosis.org/AP180/AP180.html +
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| http://dbpedia.org/ontology/wikiPageID
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6910971
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| http://dbpedia.org/ontology/wikiPageLength
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2699
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| http://dbpedia.org/ontology/wikiPageRevisionID
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977927763
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| http://dbpedia.org/ontology/wikiPageWikiLink
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http://dbpedia.org/resource/Category:Protein_domains +
, http://dbpedia.org/resource/AP180 +
, http://dbpedia.org/resource/SNAP91 +
, http://dbpedia.org/resource/PtdIns%284%2C5%29P2 +
, http://dbpedia.org/resource/PICALM +
, http://dbpedia.org/resource/HIP1R +
, http://dbpedia.org/resource/HIP1 +
, http://dbpedia.org/resource/Category:Peripheral_membrane_proteins +
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| http://dbpedia.org/property/caption
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Clathrin assembly lymphoid myeloid leukemia protein
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| http://dbpedia.org/property/cdd
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cd03564
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| http://dbpedia.org/property/interpro
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IPR011417
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| http://dbpedia.org/property/name
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ANTH domain
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| http://dbpedia.org/property/opmFamily
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38
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| http://dbpedia.org/property/opmProtein
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1
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| http://dbpedia.org/property/pfam
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PF07651
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| http://dbpedia.org/property/symbol
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ANTH
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| http://dbpedia.org/property/wikiPageUsesTemplate
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http://dbpedia.org/resource/Template:Cite_journal +
, http://dbpedia.org/resource/Template:Pfam_box +
, http://dbpedia.org/resource/Template:UMichOPM +
, http://dbpedia.org/resource/Template:Reflist +
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| http://purl.org/dc/terms/subject
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http://dbpedia.org/resource/Category:Protein_domains +
, http://dbpedia.org/resource/Category:Peripheral_membrane_proteins +
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| http://purl.org/linguistics/gold/hypernym
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http://dbpedia.org/resource/Domain +
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| http://www.w3.org/ns/prov#wasDerivedFrom
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http://en.wikipedia.org/wiki/ANTH_domain?oldid=977927763&ns=0 +
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| http://xmlns.com/foaf/0.1/depiction
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http://commons.wikimedia.org/wiki/Special:FilePath/1hfa_opm.png +
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| http://xmlns.com/foaf/0.1/isPrimaryTopicOf
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http://en.wikipedia.org/wiki/ANTH_domain +
|
| owl:sameAs |
https://global.dbpedia.org/id/2LHzf +
, http://yago-knowledge.org/resource/ANTH_domain +
, http://www.wikidata.org/entity/Q24780884 +
, http://rdf.freebase.com/ns/m.0gwmls +
, http://dbpedia.org/resource/ANTH_domain +
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| rdf:type |
http://dbpedia.org/class/yago/WikicatProteinDomains +
, http://www.wikidata.org/entity/Q206229 +
, http://dbpedia.org/class/yago/Relation100031921 +
, http://dbpedia.org/class/yago/Part113809207 +
, http://dbpedia.org/class/yago/WikicatPeripheralMembraneProteins +
, http://dbpedia.org/class/yago/Macromolecule114944888 +
, http://dbpedia.org/class/yago/Matter100020827 +
, http://dbpedia.org/ontology/Protein +
, http://dbpedia.org/class/yago/Protein114728724 +
, http://dbpedia.org/class/yago/OrganicCompound114727670 +
, http://dbpedia.org/class/yago/Material114580897 +
, http://dbpedia.org/class/yago/Compound114818238 +
, http://dbpedia.org/class/yago/Chemical114806838 +
, http://dbpedia.org/class/yago/Substance100019613 +
, http://dbpedia.org/class/yago/PhysicalEntity100001930 +
, http://dbpedia.org/class/yago/Thing100002452 +
, http://dbpedia.org/class/yago/Molecule114682133 +
, http://dbpedia.org/class/yago/Abstraction100002137 +
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, http://dbpedia.org/ontology/Biomolecule +
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, http://dbpedia.org/class/yago/Sphere114514039 +
|
| rdfs:comment |
The ANTH domain is a membrane binding doma … The ANTH domain is a membrane binding domain that shows weak specificity for PtdIns(4,5)P2. It was found in AP180 (homologous to CALM) endocytotic accessory protein that has been implicated in the formation of clathrin-coated pits. The domain is involved in phosphatidylinositol 4,5-bisphosphate binding and is a universal adaptor for nucleation of clathrin coats. Its structure is a solenoid of 9 helices. The PtdIns(4,5)P2 binding residues are spread over several helices at the tip of the structure. The PtdIns(4,5)P2 binding sequence is Kx9Kx(K/R)(H/Y).,5)P2 binding sequence is Kx9Kx(K/R)(H/Y).
|
| rdfs:label |
ANTH domain
|
